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HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy.
Hussain K, Liu R, Smith RCG, Müller KTJ, Ghorbani M, Macari S, Cleary KLS, Oldham RJ, Foxall RB, James S, Booth SG, Murray T, Dahal LN, Hargreaves CE, Kemp RS, Longley J, Douglas J, Markham H, Chee SJ, Stopforth RJ, Roghanian A, Carter MJ, Ottensmeier CH, Frendéus B, Cutress RI, French RR, Glennie MJ, Strefford JC, Thirdborough SM, Beers SA, Cragg MS. Hussain K, et al. Among authors: stopforth rj. J Exp Clin Cancer Res. 2022 Apr 7;41(1):131. doi: 10.1186/s13046-022-02294-5. J Exp Clin Cancer Res. 2022. PMID: 35392965 Free PMC article.
Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB.
Stopforth RJ, Cleary KL, Cragg MS. Stopforth RJ, et al. J Clin Immunol. 2016 May;36 Suppl 1:88-94. doi: 10.1007/s10875-016-0247-8. Epub 2016 Feb 27. J Clin Immunol. 2016. PMID: 26922075 Free PMC article. Review.
Shaving Is an Epiphenomenon of Type I and II Anti-CD20-Mediated Phagocytosis, whereas Antigenic Modulation Limits Type I Monoclonal Antibody Efficacy.
Dahal LN, Huang CY, Stopforth RJ, Mead A, Chan K, Bowater JX, Taylor MC, Narang P, Chan HTC, Kim JH, Vaughan AT, Forconi F, Beers SA. Dahal LN, et al. Among authors: stopforth rj. J Immunol. 2018 Aug 15;201(4):1211-1221. doi: 10.4049/jimmunol.1701122. Epub 2018 Jul 11. J Immunol. 2018. PMID: 29997125 Free PMC article.