Rosenthal PJ - Search Results

1

Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.

Lopes EA, Mestre R, Fontinha D, Legac J, Pei JV, Sanches-Vaz M, Mori M, Lehane AM, Rosenthal PJ, Prudêncio M, Santos MMM. Lopes EA, et al. Among authors: rosenthal pj. Eur J Med Chem. 2022 Jun 5;236:114324. doi: 10.1016/j.ejmech.2022.114324. Epub 2022 Mar 28. Eur J Med Chem. 2022. PMID: 35390711

2

Stage-specific antimalarial activity of cysteine protease inhibitors.

Shenai BR, Semenov AV, Rosenthal PJ. Shenai BR, et al. Among authors: rosenthal pj. Biol Chem. 2002 May;383(5):843-7. doi: 10.1515/BC.2002.089. Biol Chem. 2002. PMID: 12108550

3

Antimalarial drug discovery: old and new approaches.

Rosenthal PJ. Rosenthal PJ. J Exp Biol. 2003 Nov;206(Pt 21):3735-44. doi: 10.1242/jeb.00589. J Exp Biol. 2003. PMID: 14506208 Review.

4

Antimalarial activities of novel synthetic cysteine protease inhibitors.

Lee BJ, Singh A, Chiang P, Kemp SJ, Goldman EA, Weinhouse MI, Vlasuk GP, Rosenthal PJ. Lee BJ, et al. Among authors: rosenthal pj. Antimicrob Agents Chemother. 2003 Dec;47(12):3810-4. doi: 10.1128/AAC.47.12.3810-3814.2003. Antimicrob Agents Chemother. 2003. PMID: 14638488 Free PMC article.

5

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.

Greenbaum DC, Mackey Z, Hansell E, Doyle P, Gut J, Caffrey CR, Lehrman J, Rosenthal PJ, McKerrow JH, Chibale K. Greenbaum DC, et al. Among authors: rosenthal pj. J Med Chem. 2004 Jun 3;47(12):3212-9. doi: 10.1021/jm030549j. J Med Chem. 2004. PMID: 15163200

6

Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport.

Singh A, Rosenthal PJ. Singh A, et al. Among authors: rosenthal pj. J Biol Chem. 2004 Aug 20;279(34):35236-41. doi: 10.1074/jbc.M404235200. Epub 2004 Jun 10. J Biol Chem. 2004. PMID: 15192087 Free article.

7

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.

Fujii N, Mallari JP, Hansell EJ, Mackey Z, Doyle P, Zhou YM, Gut J, Rosenthal PJ, McKerrow JH, Guy RK. Fujii N, et al. Among authors: rosenthal pj. Bioorg Med Chem Lett. 2005 Jan 3;15(1):121-3. doi: 10.1016/j.bmcl.2004.10.023. Bioorg Med Chem Lett. 2005. PMID: 15582423

8

Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.

Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M. Desai PV, et al. J Med Chem. 2004 Dec 16;47(26):6609-15. doi: 10.1021/jm0493717. J Med Chem. 2004. PMID: 15588096

9

Synthesis and evaluation of new antimalarial phenylurenyl chalcone derivatives.

Domínguez JN, León C, Rodrigues J, Gamboa de Domínguez N, Gut J, Rosenthal PJ. Domínguez JN, et al. Among authors: rosenthal pj. J Med Chem. 2005 May 19;48(10):3654-8. doi: 10.1021/jm058208o. J Med Chem. 2005. PMID: 15887974

10

Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors.

Parikh S, Gut J, Istvan E, Goldberg DE, Havlir DV, Rosenthal PJ. Parikh S, et al. Among authors: rosenthal pj. Antimicrob Agents Chemother. 2005 Jul;49(7):2983-5. doi: 10.1128/AAC.49.7.2983-2985.2005. Antimicrob Agents Chemother. 2005. PMID: 15980379 Free PMC article.

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