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Page 1
Structural Biology and Protein Engineering of Thrombolytics.
Mican J, Toul M, Bednar D, Damborsky J. Mican J, et al. Comput Struct Biotechnol J. 2019 Jul 2;17:917-938. doi: 10.1016/j.csbj.2019.06.023. eCollection 2019. Comput Struct Biotechnol J. 2019. PMID: 31360331 Free PMC article. Review.
Development and Testing of Thrombolytics in Stroke.
Nikitin D, Choi S, Mican J, Toul M, Ryu WS, Damborsky J, Mikulik R, Kim DE. Nikitin D, et al. Among authors: mican j. J Stroke. 2021 Jan;23(1):12-36. doi: 10.5853/jos.2020.03349. Epub 2021 Jan 31. J Stroke. 2021. PMID: 33600700 Free PMC article. Review.
Mechanism-Based Design of Efficient PET Hydrolases.
Wei R, von Haugwitz G, Pfaff L, Mican J, Badenhorst CPS, Liu W, Weber G, Austin HP, Bednar D, Damborsky J, Bornscheuer UT. Wei R, et al. Among authors: mican j. ACS Catal. 2022 Mar 18;12(6):3382-3396. doi: 10.1021/acscatal.1c05856. Epub 2022 Feb 28. ACS Catal. 2022. PMID: 35368328 Free PMC article. Review.
Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Pfaff L, Gao J, Li Z, Jäckering A, Weber G, Mican J, Chen Y, Dong W, Han X, Feiler CG, Ao YF, Badenhorst CPS, Bednar D, Palm GJ, Lammers M, Damborsky J, Strodel B, Liu W, Bornscheuer UT, Wei R. Pfaff L, et al. Among authors: mican j. ACS Catal. 2022 Aug 5;12(15):9790-9800. doi: 10.1021/acscatal.2c02275. Epub 2022 Jul 27. ACS Catal. 2022. PMID: 35966606 Free PMC article.
Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization.
von Haugwitz G, Han X, Pfaff L, Li Q, Wei H, Gao J, Methling K, Ao Y, Brack Y, Mican J, Feiler CG, Weiss MS, Bednar D, Palm GJ, Lalk M, Lammers M, Damborsky J, Weber G, Liu W, Bornscheuer UT, Wei R. von Haugwitz G, et al. Among authors: mican j. ACS Catal. 2022 Dec 16;12(24):15259-15270. doi: 10.1021/acscatal.2c03772. Epub 2022 Nov 29. ACS Catal. 2022. PMID: 36570084 Free PMC article.
A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C.
Boyer PL, Rehm CA, Sneller MC, Mican J, Caplan MR, Dewar R, Ferris AL, Clark P, Johnson A, Maldarelli F, Hughes SH. Boyer PL, et al. Among authors: mican j. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0150021. doi: 10.1128/AAC.01500-21. Epub 2021 Nov 1. Antimicrob Agents Chemother. 2022. PMID: 34723625 Free PMC article.
78 results