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TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial.
Svensson EC, Madar A, Campbell CD, He Y, Sultan M, Healey ML, Xu H, D'Aco K, Fernandez A, Wache-Mainier C, Libby P, Ridker PM, Beste MT, Basson CT. Svensson EC, et al. Among authors: madar a. JAMA Cardiol. 2022 May 1;7(5):521-528. doi: 10.1001/jamacardio.2022.0386. JAMA Cardiol. 2022. PMID: 35385050 Free PMC article. Clinical Trial.
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial.
Xu H, Hon C, Kaiser S, Serrano-Fernandez P, Hartmann N, Yates DP, Healey M, Gusev AI, Laramie JM, Kennedy S, Marc P, Ridker PM, Obeidat M, Beste MT, Svensson EC, Madar A. Xu H, et al. Among authors: madar a. Circ Genom Precis Med. 2021 Dec;14(6):e003440. doi: 10.1161/CIRCGEN.121.003440. Epub 2021 Oct 19. Circ Genom Precis Med. 2021. PMID: 34663088 No abstract available.
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection.
Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Wang C, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Bhattacharya R, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Kiryluk K, Neale B, Ionita-Laza I, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ; Biobank Japan Project; FinnGen Consortium; Terao C, Zhao H, Ebert BL, Reilly MP, Ganna A, Machiela MJ, Genovese G, Natarajan P. Zekavat SM, et al. Nat Med. 2021 Jun;27(6):1012-1024. doi: 10.1038/s41591-021-01371-0. Epub 2021 Jun 7. Nat Med. 2021. PMID: 34099924 Free PMC article.
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells.
Guedan S, Chen X, Madar A, Carpenito C, McGettigan SE, Frigault MJ, Lee J, Posey AD Jr, Scholler J, Scholler N, Bonneau R, June CH. Guedan S, et al. Among authors: madar a. Blood. 2014 Aug 14;124(7):1070-80. doi: 10.1182/blood-2013-10-535245. Epub 2014 Jul 1. Blood. 2014. PMID: 24986688 Free PMC article.
83 results