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Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci.
Satofuka H, Abe S, Moriwaki T, Okada A, Kazuki K, Tanaka H, Yamazaki K, Hichiwa G, Morimoto K, Takayama H, Nakayama Y, Hatano S, Yada Y, Murakami Y, Baba Y, Oshimura M, Tomizuka K, Kazuki Y. Satofuka H, et al. Among authors: tomizuka k. Nat Commun. 2022 Apr 5;13(1):1841. doi: 10.1038/s41467-022-29421-2. Nat Commun. 2022. PMID: 35383174 Free PMC article.
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.
Kazuki Y, Kobayashi K, Aueviriyavit S, Oshima T, Kuroiwa Y, Tsukazaki Y, Senda N, Kawakami H, Ohtsuki S, Abe S, Takiguchi M, Hoshiya H, Kajitani N, Takehara S, Kubo K, Terasaki T, Chiba K, Tomizuka K, Oshimura M. Kazuki Y, et al. Among authors: tomizuka k. Hum Mol Genet. 2013 Feb 1;22(3):578-92. doi: 10.1093/hmg/dds468. Epub 2012 Nov 2. Hum Mol Genet. 2013. PMID: 23125282
Panel of human cell lines with human/mouse artificial chromosomes.
Uno N, Takata S, Komoto S, Miyamoto H, Nakayama Y, Osaki M, Mayuzumi R, Miyazaki N, Hando C, Abe S, Sakuma T, Yamamoto T, Suzuki T, Nakajima Y, Oshimura M, Tomizuka K, Kazuki Y. Uno N, et al. Among authors: tomizuka k. Sci Rep. 2022 Feb 22;12(1):3009. doi: 10.1038/s41598-022-06814-3. Sci Rep. 2022. PMID: 35194085 Free PMC article.
Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling.
Kazuki Y, Uno N, Abe S, Kajitani N, Kazuki K, Yakura Y, Sawada C, Takata S, Sugawara M, Nagashima Y, Okada A, Hiratsuka M, Osaki M, Ferrari G, Tedesco FS, Nishikawa S, Fukumoto K, Takayanagi SI, Kunisato A, Kaneko S, Oshimura M, Tomizuka K. Kazuki Y, et al. Among authors: tomizuka k. Mol Ther Nucleic Acids. 2020 Dec 19;23:629-639. doi: 10.1016/j.omtn.2020.12.012. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2020. PMID: 33552683 Free PMC article.
86 results