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Urinary Proteomics Identifies Cathepsin D as a Biomarker of Rapid eGFR Decline in Type 1 Diabetes.
Limonte CP, Valo E, Drel V, Natarajan L, Darshi M, Forsblom C, Henderson CM, Hoofnagle AN, Ju W, Kretzler M, Montemayor D, Nair V, Nelson RG, O'Toole JF, Toto RD, Rosas SE, Ruzinski J, Sandholm N, Schmidt IM, Vaisar T, Waikar SS, Zhang J, Rossing P, Ahluwalia TS, Groop PH, Pennathur S, Snell-Bergeon JK, Costacou T, Orchard TJ, Sharma K, de Boer IH; Kidney Precision Medicine Project. Limonte CP, et al. Among authors: sharma k. Diabetes Care. 2022 Jun 2;45(6):1416-1427. doi: 10.2337/dc21-2204. Diabetes Care. 2022. PMID: 35377940 Free PMC article.
Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease.
Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK. Sharma K, et al. Among authors: sharma s. J Am Soc Nephrol. 2013 Nov;24(11):1901-12. doi: 10.1681/ASN.2013020126. Epub 2013 Oct 10. J Am Soc Nephrol. 2013. PMID: 23949796 Free PMC article.
Dipeptidyl peptidase-4 inhibition with linagliptin and effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: Rationale and design of the MARLINA-T2D™ trial.
Groop PH, Cooper ME, Perkovic V, Sharma K, Schernthaner G, Haneda M, Hocher B, Gordat M, Cescutti J, Woerle HJ, von Eynatten M. Groop PH, et al. Among authors: sharma k. Diab Vasc Dis Res. 2015 Nov;12(6):455-62. doi: 10.1177/1479164115579002. Epub 2015 Jul 28. Diab Vasc Dis Res. 2015. PMID: 26224765 Free article. Clinical Trial.
Diabetic kidney disease.
Thomas MC, Brownlee M, Susztak K, Sharma K, Jandeleit-Dahm KA, Zoungas S, Rossing P, Groop PH, Cooper ME. Thomas MC, et al. Among authors: sharma k. Nat Rev Dis Primers. 2015 Jul 30;1:15018. doi: 10.1038/nrdp.2015.18. Nat Rev Dis Primers. 2015. PMID: 27188921 Free PMC article. Review.
Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications.
Sas KM, Kayampilly P, Byun J, Nair V, Hinder LM, Hur J, Zhang H, Lin C, Qi NR, Michailidis G, Groop PH, Nelson RG, Darshi M, Sharma K, Schelling JR, Sedor JR, Pop-Busui R, Weinberg JM, Soleimanpour SA, Abcouwer SF, Gardner TW, Burant CF, Feldman EL, Kretzler M, Brosius FC 3rd, Pennathur S. Sas KM, et al. Among authors: sharma k. JCI Insight. 2016 Sep 22;1(15):e86976. doi: 10.1172/jci.insight.86976. JCI Insight. 2016. PMID: 27699244 Free PMC article.
Systems biology analysis reveals role of MDM2 in diabetic nephropathy.
Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JCI, Anders HJ, Sharma K. Saito R, et al. Among authors: sharma k. JCI Insight. 2016 Oct 20;1(17):e87877. doi: 10.1172/jci.insight.87877. JCI Insight. 2016. PMID: 27777973 Free PMC article.
4,637 results