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Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis.
Madrigal-Aguilar DA, Gonzalez-Silva A, Rosales-Acosta B, Bautista-Crescencio C, Ortiz-Álvarez J, Escalante CH, Sánchez-Navarrete J, Hernández-Rodríguez C, Chamorro-Cevallos G, Tamariz J, Villa-Tanaca L. Madrigal-Aguilar DA, et al. Among authors: escalante ch. Microbiol Spectr. 2022 Apr 27;10(2):e0164221. doi: 10.1128/spectrum.01642-21. Epub 2022 Apr 4. Microbiol Spectr. 2022. PMID: 35377226 Free PMC article.
Enantiopure 4-oxazolin-2-ones and 4-methylene-2-oxazolidinones as chiral building blocks in a divergent asymmetric synthesis of heterocycles.
Santoyo BM, González-Romero C, Zárate-Zárate D, Hernández-Benitez RI, Pelayo V, Barrera E, Escalante CH, Fuentes-Benites A, Martínez-Morales G, López J, Vázquez MA, Delgado F, Jiménez-Vázquez HA, Tamariz J. Santoyo BM, et al. Among authors: escalante ch. Chirality. 2019 Sep;31(9):719-749. doi: 10.1002/chir.23109. Epub 2019 Jul 18. Chirality. 2019. PMID: 31318100
Synthesis and highly potent anti-inflammatory activity of licofelone- and ketorolac-based 1-arylpyrrolizin-3-ones.
Madrigal DA, Escalante CH, Gutiérrez-Rebolledo GA, Cristobal-Luna JM, Gómez-García O, Hernández-Benitez RI, Esquivel-Campos AL, Pérez-Gutiérrez S, Chamorro-Cevallos GA, Delgado F, Tamariz J. Madrigal DA, et al. Among authors: escalante ch. Bioorg Med Chem. 2019 Oct 15;27(20):115053. doi: 10.1016/j.bmc.2019.115053. Epub 2019 Aug 20. Bioorg Med Chem. 2019. PMID: 31471100
Three-Component Synthesis of 2-Amino-3-cyano-4H-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing.
Feliciano A, Gómez-García O, Escalante CH, Rodríguez-Hernández MA, Vargas-Fuentes M, Andrade-Pavón D, Villa-Tanaca L, Álvarez-Toledano C, Ramírez-Apan MT, Vázquez MA, Tamariz J, Delgado F. Feliciano A, et al. Among authors: escalante ch. Pharmaceuticals (Basel). 2021 Oct 30;14(11):1110. doi: 10.3390/ph14111110. Pharmaceuticals (Basel). 2021. PMID: 34832892 Free PMC article.
Divergent Pd-catalyzed Functionalization of 4-Oxazolin-2-ones and 4-Methylene-2-oxazolidinones and Synthesis of Heterocyclic-Fused Indoles.
Yescas-Galicia D, Restrepo-Osorio RA, García-González AN, Hernández-Benítez RI, Espinoza-Hicks JC, Escalante CH, Barrera E, Santoyo BM, Delgado F, Tamariz J. Yescas-Galicia D, et al. Among authors: escalante ch. J Org Chem. 2022 Oct 7;87(19):13034-13052. doi: 10.1021/acs.joc.2c01563. Epub 2022 Sep 26. J Org Chem. 2022. PMID: 36153994
Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors.
Aguila-Muñoz DG, Vázquez-Lira G, Sarmiento-Tlale E, Cruz-López MC, Jiménez-Montejo FE, López Y López VE, Escalante CH, Andrade-Pavón D, Gómez-García O, Tamariz J, Mendieta-Moctezuma A. Aguila-Muñoz DG, et al. Among authors: escalante ch. Molecules. 2023 May 18;28(10):4180. doi: 10.3390/molecules28104180. Molecules. 2023. PMID: 37241920 Free PMC article.