Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution.
Chen G, Gong T, Wang Z, Wang Z, Lin X, Chen S, Sun C, Zhao W, Kong Y, Ai H, Yang H, Liu Y, Wu F, Kang J, Zhao S, Xiao X, Sun J, He A, Li Z.
Chen G, et al. Among authors: he a.
Cell Oncol (Dordr). 2022 Dec;45(6):1155-1167. doi: 10.1007/s13402-022-00705-5. Epub 2022 Sep 22.
Cell Oncol (Dordr). 2022.
PMID: 36136268
PURPOSE: Oxaliplatin-based chemotherapy is a standard treatment for advanced colorectal cancer (CRC) patients. ...CRC-PDOs well recapitulated the morphology and histology of their parental biopsies based on HE and IHC staining of pathological biomarkers. The scRNA-S …
PURPOSE: Oxaliplatin-based chemotherapy is a standard treatment for advanced colorectal cancer (CRC) patients. ...CRC-PDOs well recap …