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Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses.
Rodríguez-Ubreva J, Arutyunyan A, Bonder MJ, Del Pino-Molina L, Clark SJ, de la Calle-Fabregat C, Garcia-Alonso L, Handfield LF, Ciudad L, Andrés-León E, Krueger F, Català-Moll F, Rodríguez-Cortez VC, Polanski K, Mamanova L, van Dongen S, Kiselev VY, Martínez-Saavedra MT, Heyn H, Martín J, Warnatz K, López-Granados E, Rodríguez-Gallego C, Stegle O, Kelsey G, Vento-Tormo R, Ballestar E. Rodríguez-Ubreva J, et al. Among authors: rodriguez cortez vc. Nat Commun. 2022 Apr 1;13(1):1779. doi: 10.1038/s41467-022-29450-x. Nat Commun. 2022. PMID: 35365635 Free PMC article.
Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition.
Rodríguez-Cortez VC, Del Pino-Molina L, Rodríguez-Ubreva J, Ciudad L, Gómez-Cabrero D, Company C, Urquiza JM, Tegnér J, Rodríguez-Gallego C, López-Granados E, Ballestar E. Rodríguez-Cortez VC, et al. Nat Commun. 2015 Jun 17;6:7335. doi: 10.1038/ncomms8335. Nat Commun. 2015. PMID: 26081581 Free PMC article.
Dissecting Epigenetic Dysregulation of Primary Antibody Deficiencies.
Rodríguez-Cortez VC, Del Pino-Molina L, Rodríguez-Ubreva J, López-Granados E, Ballestar E. Rodríguez-Cortez VC, et al. J Clin Immunol. 2016 May;36 Suppl 1:48-56. doi: 10.1007/s10875-016-0267-4. Epub 2016 Mar 17. J Clin Immunol. 2016. PMID: 26984849 Review.
Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.
Rodríguez-Cortez VC, Martínez-Redondo P, Català-Moll F, Rodríguez-Ubreva J, Garcia-Gomez A, Poorani-Subramani G, Ciudad L, Hernando H, Pérez-García A, Company C, Urquiza JM, Ramiro AR, Di Noia JM, Vaquero A, Ballestar E. Rodríguez-Cortez VC, et al. Sci Rep. 2017 Aug 8;7(1):7594. doi: 10.1038/s41598-017-07380-9. Sci Rep. 2017. PMID: 28790320 Free PMC article.
Epigenomic deregulation in the immune system.
Rodriguez-Cortez VC, Hernando H, de la Rica L, Vento R, Ballestar E. Rodriguez-Cortez VC, et al. Epigenomics. 2011 Dec;3(6):697-713. doi: 10.2217/epi.11.99. Epigenomics. 2011. PMID: 22126290 Review.
The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion.
Hernando H, Shannon-Lowe C, Islam AB, Al-Shahrour F, Rodríguez-Ubreva J, Rodríguez-Cortez VC, Javierre BM, Mangas C, Fernández AF, Parra M, Delecluse HJ, Esteller M, López-Granados E, Fraga MF, López-Bigas N, Ballestar E. Hernando H, et al. Among authors: rodriguez cortez vc. Genome Biol. 2013 Jan 15;14(1):R3. doi: 10.1186/gb-2013-14-1-r3. Genome Biol. 2013. PMID: 23320978 Free PMC article.
Two independent epigenetic biomarkers predict survival in neuroblastoma.
Yáñez Y, Grau E, Rodríguez-Cortez VC, Hervás D, Vidal E, Noguera R, Hernández M, Segura V, Cañete A, Conesa A, Font de Mora J, Castel V. Yáñez Y, et al. Among authors: rodriguez cortez vc. Clin Epigenetics. 2015 Feb 27;7(1):16. doi: 10.1186/s13148-015-0054-8. eCollection 2015. Clin Epigenetics. 2015. PMID: 25767620 Free PMC article.
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.
García-Castillo J, Alcaraz-Pérez F, Martínez-Balsalobre E, García-Moreno D, Rossmann MP, Fernández-Lajarín M, Bernabé-García M, Pérez-Oliva AB, Rodríguez-Cortez VC, Bueno C, Adatto I, Agarwal S, Menéndez P, Zon LI, Mulero V, Cayuela ML. García-Castillo J, et al. Among authors: rodriguez cortez vc. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2015528118. doi: 10.1073/pnas.2015528118. Proc Natl Acad Sci U S A. 2021. PMID: 34353901 Free PMC article.
13 results