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Tankyrase represses autoinflammation through the attenuation of TLR2 signaling.
Matsumoto Y, Dimitriou ID, La Rose J, Lim M, Camilleri S, Law N, Adissu HA, Tong J, Moran MF, Chruscinski A, He F, Asano Y, Katsuyama T, Sada KE, Wada J, Rottapel R. Matsumoto Y, et al. Among authors: chruscinski a. J Clin Invest. 2022 Apr 1;132(7):e140869. doi: 10.1172/JCI140869. J Clin Invest. 2022. PMID: 35362478 Free PMC article.
Inhibition of the Fibrinogen-Like Protein 2:FcγRIIB/RIII immunosuppressive pathway enhances antiviral T-cell and B-cell responses leading to clearance of lymphocytic choriomeningitis virus clone 13.
Luft O, Khattar R, Farrokhi K, Ferri D, Yavorska N, Zhang J, Sadozai H, Adeyi O, Chruscinski A, Levy GA, Selzner N. Luft O, et al. Among authors: chruscinski a. Immunology. 2018 Jul;154(3):476-489. doi: 10.1111/imm.12897. Epub 2018 Feb 20. Immunology. 2018. PMID: 29341118 Free PMC article.
Serological abnormalities that predict progression to systemic autoimmune rheumatic diseases in antinuclear antibody-positive individuals.
Muñoz-Grajales C, Prokopec SD, Johnson SR, Touma Z, Ahmad Z, Bonilla D, Hiraki L, Bookman A, Boutros PC, Chruscinski A, Wither J. Muñoz-Grajales C, et al. Among authors: chruscinski a. Rheumatology (Oxford). 2022 Mar 2;61(3):1092-1105. doi: 10.1093/rheumatology/keab501. Rheumatology (Oxford). 2022. PMID: 34175923 Free PMC article.
Evaluation of a gene expression biomarker to identify operationally tolerant liver transplant recipients: the LITMUS trial.
Chruscinski A, Rojas-Luengas V, Moshkelgosha S, Issachar A, Luo J, Yowanto H, Lilly L, Smith R, Renner E, Zhang J, Epstein M, Grant D, McEvoy CM, Konvalinka A, Humar A, Adeyi O, Fischer S, Volmer FH, Taubert R, Jaeckel E, Juvet S, Selzner N, Levy GA. Chruscinski A, et al. Clin Exp Immunol. 2022 Jan 28;207(1):123-139. doi: 10.1093/cei/uxab011. Clin Exp Immunol. 2022. PMID: 35020854 Free PMC article. Clinical Trial.
Congenic hematopoietic stem cell transplantation promotes survival of heart allografts in murine models of acute and chronic rejection.
Sadozai H, Rojas-Luengas V, Farrokhi K, Moshkelgosha S, Guo Q, He W, Li A, Zhang J, Chua C, Ferri D, Mian M, Adeyi O, Seidman M, Gorczynski RM, Juvet S, Atkins H, Levy GA, Chruscinski A. Sadozai H, et al. Among authors: chruscinski a. Clin Exp Immunol. 2023 Jul 5;213(1):138-154. doi: 10.1093/cei/uxad038. Clin Exp Immunol. 2023. PMID: 37004176 Free PMC article.
The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts.
Urbanellis P, Shyu W, Khattar R, Wang J, Zakharova A, He W, Sadozai H, Amir AZ, Shalev I, Phillips MJ, Adeyi O, Ross H, Grant D, Levy GA, Chruscinski A. Urbanellis P, et al. Among authors: chruscinski a. Immunology. 2015 Jan;144(1):91-106. doi: 10.1111/imm.12354. Immunology. 2015. PMID: 24990517 Free PMC article.
Overexpression of Fibrinogen-Like Protein 2 Promotes Tolerance in a Fully Mismatched Murine Model of Heart Transplantation.
Bartczak A, Chruscinski A, Mendicino M, Liu H, Zhang J, He W, Amir AZ, Nguyen A, Khattar R, Sadozai H, Lobe CG, Adeyi O, Phillips MJ, Zhang L, Gorczynski RM, Grant D, Levy GA. Bartczak A, et al. Among authors: chruscinski a. Am J Transplant. 2016 Jun;16(6):1739-50. doi: 10.1111/ajt.13696. Epub 2016 Mar 17. Am J Transplant. 2016. PMID: 26718313 Free article.
41 results