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Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy.
Meng XW, Heldebrant MP, Flatten KS, Loegering DA, Dai H, Schneider PA, Gomez TS, Peterson KL, Trushin SA, Hess AD, Smith BD, Karp JE, Billadeau DD, Kaufmann SH. Meng XW, et al. Among authors: kaufmann sh. J Biol Chem. 2010 Jan 8;285(2):888-902. doi: 10.1074/jbc.M109.057638. Epub 2009 Nov 3. J Biol Chem. 2010. PMID: 19887445 Free PMC article.
Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation.
Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Sainski AM, et al. Among authors: kaufmann sh. J Cell Biol. 2014 Sep 29;206(7):867-76. doi: 10.1083/jcb.201405051. Epub 2014 Sep 22. J Cell Biol. 2014. PMID: 25246614 Free PMC article.
COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.
Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein MY, Wallis M, McGaughran J, Gecz J, Sluis Bv, Billadeau DD, Burstein E. Phillips-Krawczak CA, et al. Among authors: kaufmann sh. Mol Biol Cell. 2015 Jan 1;26(1):91-103. doi: 10.1091/mbc.E14-06-1073. Epub 2014 Oct 29. Mol Biol Cell. 2015. PMID: 25355947 Free PMC article.
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Correia C, Schneider PA, Dai H, Dogan A, Maurer MJ, Church AK, Novak AJ, Feldman AL, Wu X, Ding H, Meng XW, Cerhan JR, Slager SL, Macon WR, Habermann TM, Karp JE, Gore SD, Kay NE, Jelinek DF, Witzig TE, Nowakowski GS, Kaufmann SH. Correia C, et al. Among authors: kaufmann sh. Blood. 2015 Jan 22;125(4):658-67. doi: 10.1182/blood-2014-04-571786. Epub 2014 Dec 1. Blood. 2015. PMID: 25452615 Free PMC article. Clinical Trial.
1,196 results