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Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa.
Renau TE, Léger R, Filonova L, Flamme EM, Wang M, Yen R, Madsen D, Griffith D, Chamberland S, Dudley MN, Lee VJ, Lomovskaya O, Watkins WJ, Ohta T, Nakayama K, Ishida Y. Renau TE, et al. Among authors: lomovskaya o. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2755-8. doi: 10.1016/s0960-894x(03)00556-0. Bioorg Med Chem Lett. 2003. PMID: 12873508
Vacuuming the periplasm.
Lomovskaya O, Totrov M. Lomovskaya O, et al. J Bacteriol. 2005 Mar;187(6):1879-83. doi: 10.1128/JB.187.6.1879-1883.2005. J Bacteriol. 2005. PMID: 15743933 Free PMC article. Review. No abstract available.
Pharmacodynamics of levofloxacin against Pseudomonas aeruginosa with reduced susceptibility due to different efflux pumps: do elevated MICs always predict reduced in vivo efficacy?
Griffith DC, Corcoran E, Lofland D, Lee A, Cho D, Lomovskaya O, Dudley MN. Griffith DC, et al. Among authors: lomovskaya o. Antimicrob Agents Chemother. 2006 May;50(5):1628-32. doi: 10.1128/AAC.50.5.1628-1632.2006. Antimicrob Agents Chemother. 2006. PMID: 16641428 Free PMC article.
Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization.
Watkins WJ, Chong L, Cho A, Hilgenkamp R, Ludwikow M, Garizi N, Iqbal N, Barnard J, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Kumaraswamy P, Blecken A, Bai S, Loury DJ, Griffith DC, Dudley MN. Watkins WJ, et al. Among authors: lomovskaya o. Bioorg Med Chem Lett. 2007 May 15;17(10):2802-6. doi: 10.1016/j.bmcl.2007.02.047. Epub 2007 Feb 27. Bioorg Med Chem Lett. 2007. PMID: 17350259
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections.
Tsivkovskii R, Sabet M, Tarazi Z, Griffith DC, Lomovskaya O, Dudley MN. Tsivkovskii R, et al. Among authors: lomovskaya o. FEMS Immunol Med Microbiol. 2011 Mar;61(2):141-6. doi: 10.1111/j.1574-695X.2010.00755.x. Epub 2010 Nov 12. FEMS Immunol Med Microbiol. 2011. PMID: 21073547 Free article.
77 results