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Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Hulikova A, Park KC, Loonat AA, Gunadasa-Rohling M, Curtis MK, Chung YJ, Wilson A, Carr CA, Trafford AW, Fournier M, Moshnikova A, Andreev OA, Reshetnyak YK, Riley PR, Smart N, Milne TA, Crump NT, Swietach P. Hulikova A, et al. Among authors: curtis mk. Basic Res Cardiol. 2022 Mar 31;117(1):17. doi: 10.1007/s00395-022-00924-9. Basic Res Cardiol. 2022. PMID: 35357563 Free PMC article.
Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.
Wilson AD, Richards MA, Curtis MK, Gunadasa-Rohling M, Monterisi S, Loonat AA, Miller JJ, Ball V, Lewis A, Tyler DJ, Moshnikova A, Andreev OA, Reshetnyak YK, Carr C, Swietach P. Wilson AD, et al. Among authors: curtis mk. Cardiovasc Res. 2022 Nov 10;118(14):2946-2959. doi: 10.1093/cvr/cvab364. Cardiovasc Res. 2022. PMID: 34897412 Free PMC article.
Publisher Correction: Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation.
Frise MC, Holdsworth DA, Johnson AW, Chung YJ, Curtis MK, Cox PJ, Clarke K, Tyler DJ, Roberts DJ, Ratcliffe PJ, Dorrington KL, Robbins PA. Frise MC, et al. Among authors: curtis mk. Sci Rep. 2022 Mar 1;12(1):3685. doi: 10.1038/s41598-022-06694-7. Sci Rep. 2022. PMID: 35232980 Free PMC article. No abstract available.
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.
Park KC, Crump NT, Louwman N, Krywawych S, Cheong YJ, Vendrell I, Gill EK, Gunadasa-Rohling M, Ford KL, Hauton D, Fournier M, Pires E, Watson L, Roseman G, Holder J, Koschinski A, Carnicer R, Curtis MK, Zaccolo M, Hulikova A, Fischer R, Kramer HB, McCullagh JSO, Trefely S, Milne TA, Swietach P. Park KC, et al. Among authors: curtis mk. Nat Cardiovasc Res. 2023 Dec;2(12):1221-1245. doi: 10.1038/s44161-023-00365-0. Epub 2023 Nov 23. Nat Cardiovasc Res. 2023. PMID: 38500966 Free PMC article.
20 results