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Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections.
Sykes DB, Martinelli MM, Negoro P, Xu S, Maxcy K, Timmer K, Viens AL, Alexander NJ, Atallah J, Snarr BD, Baistrocchi SR, Atallah NJ, Hopke A, Scherer A, Rosales I, Irimia D, Sheppard DC, Mansour MK. Sykes DB, et al. J Leukoc Biol. 2022 Jun;111(6):1133-1145. doi: 10.1002/JLB.4HI1221-722R. Epub 2022 Mar 31. J Leukoc Biol. 2022. PMID: 35355310 Free PMC article.
Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes.
Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM. Mansour MK, et al. Among authors: sykes db. J Biol Chem. 2013 May 31;288(22):16043-54. doi: 10.1074/jbc.M113.473223. Epub 2013 Apr 22. J Biol Chem. 2013. PMID: 23609446 Free PMC article.
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin.
Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Palchaudhuri R, et al. Among authors: sykes db. Nat Biotechnol. 2016 Jul;34(7):738-45. doi: 10.1038/nbt.3584. Epub 2016 Jun 6. Nat Biotechnol. 2016. PMID: 27272386 Free PMC article.
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.
Biguanides enhance antifungal activity against Candida glabrata.
Xu S, Feliu M, Lord AK, Lukason DP, Negoro PE, Khan NS, Dagher Z, Feldman MB, Reedy JL, Steiger SN, Tam JM, Soukas AA, Sykes DB, Mansour MK. Xu S, et al. Among authors: sykes db. Virulence. 2018;9(1):1150-1162. doi: 10.1080/21505594.2018.1475798. Virulence. 2018. PMID: 29962263 Free PMC article.
Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species.
Negoro PE, Xu S, Dagher Z, Hopke A, Reedy JL, Feldman MB, Khan NS, Viens AL, Alexander NJ, Atallah NJ, Scherer AK, Dutko RA, Jeffery J, Kernien JF, Fites JS, Nett JE, Klein BS, Vyas JM, Irimia D, Sykes DB, Mansour MK. Negoro PE, et al. Among authors: sykes db. mBio. 2020 May 12;11(3):e02043-19. doi: 10.1128/mBio.02043-19. mBio. 2020. PMID: 32398316 Free PMC article.
127 results