Langenhorst J - Search Results

1

How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example.

Meyer C, Dierick I, Gauderat G, Langenhorst J, Sarr C, Leroux E, Chenel M, Fouliard S, Passier P. Meyer C, et al. Among authors: langenhorst j. Clin Pharmacol Ther. 2023 Feb;113(2):310-320. doi: 10.1002/cpt.2596. Epub 2022 Apr 27. Clin Pharmacol Ther. 2023. PMID: 35355254 Free PMC article.

2

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

Langenhorst JB, Boss J, van Kesteren C, Lalmohamed A, Kuball J, Egberts ACG, Boelens JJ, Huitema ADR, van Maarseveen EM. Langenhorst JB, et al. Br J Clin Pharmacol. 2020 Aug;86(8):1499-1509. doi: 10.1111/bcp.14256. Epub 2020 Mar 10. Br J Clin Pharmacol. 2020. PMID: 32067250 Free PMC article.

3

Simultaneous quantification of busulfan, clofarabine and F-ARA-A using isotope labelled standards and standard addition in plasma by LC-MS/MS for exposure monitoring in hematopoietic cell transplantation conditioning.

Punt AM, Langenhorst JB, Egas AC, Boelens JJ, van Kesteren C, van Maarseveen EM. Punt AM, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jun 15;1055-1056:81-85. doi: 10.1016/j.jchromb.2017.04.025. Epub 2017 Apr 15. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28445850 Free article.

4

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation.

de Koning C, Gabelich JA, Langenhorst J, Admiraal R, Kuball J, Boelens JJ, Nierkens S. de Koning C, et al. Among authors: langenhorst j. Blood Adv. 2018 Mar 13;2(5):565-574. doi: 10.1182/bloodadvances.2017015487. Blood Adv. 2018. PMID: 29535105 Free PMC article.

5

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation.

Langenhorst JB, Dorlo TPC, van Maarseveen EM, Nierkens S, Kuball J, Boelens JJ, van Kesteren C, Huitema ADR. Langenhorst JB, et al. Clin Pharmacokinet. 2019 May;58(5):627-637. doi: 10.1007/s40262-018-0715-9. Clin Pharmacokinet. 2019. PMID: 30327943 Free PMC article.

6

Innate Immune Recovery Predicts CD4⁺ T Cell Reconstitution after Hematopoietic Cell Transplantation.

de Koning C, Langenhorst J, van Kesteren C, Lindemans CA, Huitema ADR, Nierkens S, Boelens JJ. de Koning C, et al. Among authors: langenhorst j. Biol Blood Marrow Transplant. 2019 Apr;25(4):819-826. doi: 10.1016/j.bbmt.2018.10.013. Epub 2018 Oct 23. Biol Blood Marrow Transplant. 2019. PMID: 30359735 Free article.

7

The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia.

Keating AK, Langenhorst J, Wagner JE, Page KM, Veys P, Wynn RF, Stefanski H, Elfeky R, Giller R, Mitchell R, Milano F, O'Brien TA, Dahlberg A, Delaney C, Kurtzberg J, Verneris MR, Boelens JJ. Keating AK, et al. Among authors: langenhorst j. Blood Adv. 2019 Apr 9;3(7):1118-1128. doi: 10.1182/bloodadvances.2018025908. Blood Adv. 2019. PMID: 30952678 Free PMC article.

8

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

Langenhorst JB, van Kesteren C, van Maarseveen EM, Dorlo TPC, Nierkens S, Lindemans CA, de Witte MA, van Rhenen A, Raijmakers R, Bierings M, Kuball J, Huitema ADR, Boelens JJ. Langenhorst JB, et al. Blood Adv. 2019 Jul 23;3(14):2179-2187. doi: 10.1182/bloodadvances.2018029421. Blood Adv. 2019. PMID: 31324638 Free PMC article.

9

Predictors for Autoimmune Cytopenias after Allogeneic Hematopoietic Cell Transplantation in Children.

Szanto CL, Langenhorst J, de Koning C, Nierkens S, Bierings M, Huitema ADR, Lindemans CA, Boelens JJ. Szanto CL, et al. Among authors: langenhorst j. Biol Blood Marrow Transplant. 2020 Jan;26(1):114-122. doi: 10.1016/j.bbmt.2019.07.022. Epub 2019 Jul 22. Biol Blood Marrow Transplant. 2020. PMID: 31344451 Free article. Clinical Trial.

10

Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.

Xie J, Span M, van Maarseveen E, Langenhorst J, Boddy AV, Sia KCS, Sutton R, Venn N, Punt AM, Tyrrell V, Haber M, Trahair T, Lau L, Marshall GM, Lock RB. Xie J, et al. Among authors: langenhorst j. Pediatr Blood Cancer. 2020 Apr;67(4):e28133. doi: 10.1002/pbc.28133. Epub 2019 Dec 25. Pediatr Blood Cancer. 2020. PMID: 31876116

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