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α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Ghanem SS, Majbour NK, Vaikath NN, Ardah MT, Erskine D, Jensen NM, Fayyad M, Sudhakaran IP, Vasili E, Melachroinou K, Abdi IY, Poggiolini I, Santos P, Dorn A, Carloni P, Vekrellis K, Attems J, McKeith I, Outeiro TF, Jensen PH, El-Agnaf OMA. Ghanem SS, et al. Among authors: santos p. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109617119. doi: 10.1073/pnas.2109617119. Epub 2022 Mar 30. Proc Natl Acad Sci U S A. 2022. PMID: 35353605 Free PMC article.
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies.
Szegő ÉM, Dominguez-Meijide A, Gerhardt E, König A, Koss DJ, Li W, Pinho R, Fahlbusch C, Johnson M, Santos P, Villar-Piqué A, Thom T, Rizzoli S, Schmitz M, Li J, Zerr I, Attems J, Jahn O, Outeiro TF. Szegő ÉM, et al. Among authors: santos p. Cell Rep. 2019 Jul 2;28(1):65-77.e6. doi: 10.1016/j.celrep.2019.06.009. Cell Rep. 2019. PMID: 31269451 Free article.
A2A R-induced transcriptional deregulation in astrocytes: An in vitro study.
Paiva I, Carvalho K, Santos P, Cellai L, Pavlou MAS, Jain G, Gnad T, Pfeifer A, Vieau D, Fischer A, Buée L, Outeiro TF, Blum D. Paiva I, et al. Among authors: santos p. Glia. 2019 Dec;67(12):2329-2342. doi: 10.1002/glia.23688. Epub 2019 Jul 22. Glia. 2019. PMID: 31328322
Synucleinopathies: Where we are and where we need to go.
Brás IC, Dominguez-Meijide A, Gerhardt E, Koss D, Lázaro DF, Santos PI, Vasili E, Xylaki M, Outeiro TF. Brás IC, et al. J Neurochem. 2020 May;153(4):433-454. doi: 10.1111/jnc.14965. Epub 2020 Feb 19. J Neurochem. 2020. PMID: 31957016 Free article. Review.
Delayed repair of the facial nerve and its negative impacts on nerve and muscle regeneration.
Bueno CRS, Buchaim DV, Barraviera B, Ferreira RS Jr, Santos PSDS, Reis CHB, Cini MA, Kuga MC, Rosa GM, Buchaim RL. Bueno CRS, et al. Among authors: santos psds. J Venom Anim Toxins Incl Trop Dis. 2024 May 27;30:e20230093. doi: 10.1590/1678-9199-JVATITD-2023-0093. eCollection 2024. J Venom Anim Toxins Incl Trop Dis. 2024. PMID: 38808073 Free PMC article.
2,974 results