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Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein.
Castellano S, Taliani S, Milite C, Pugliesi I, Da Pozzo E, Rizzetto E, Bendinelli S, Costa B, Cosconati S, Greco G, Novellino E, Sbardella G, Stefancich G, Martini C, Da Settimo F. Castellano S, et al. J Med Chem. 2012 May 10;55(9):4506-10. doi: 10.1021/jm201703k. Epub 2012 Apr 25. J Med Chem. 2012. PMID: 22489952
Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.
Castellano S, Spannhoff A, Milite C, Dal Piaz F, Cheng D, Tosco A, Viviano M, Yamani A, Cianciulli A, Sala M, Cura V, Cavarelli J, Novellino E, Mai A, Bedford MT, Sbardella G. Castellano S, et al. J Med Chem. 2012 Nov 26;55(22):9875-90. doi: 10.1021/jm301097p. Epub 2012 Nov 2. J Med Chem. 2012. PMID: 23095008 Free PMC article.
Structure-activity relationship refinement and further assessment of 4-phenylquinazoline-2-carboxamide translocator protein ligands as antiproliferative agents in human glioblastoma tumors.
Castellano S, Taliani S, Viviano M, Milite C, Da Pozzo E, Costa B, Barresi E, Bruno A, Cosconati S, Marinelli L, Greco G, Novellino E, Sbardella G, Da Settimo F, Martini C. Castellano S, et al. J Med Chem. 2014 Mar 27;57(6):2413-28. doi: 10.1021/jm401721h. Epub 2014 Mar 17. J Med Chem. 2014. PMID: 24580635
Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.
Zanotti-Fregonara P, Zhang Y, Jenko KJ, Gladding RL, Zoghbi SS, Fujita M, Sbardella G, Castellano S, Taliani S, Martini C, Innis RB, Da Settimo F, Pike VW. Zanotti-Fregonara P, et al. Among authors: castellano s. ACS Chem Neurosci. 2014 Oct 15;5(10):963-71. doi: 10.1021/cn500138n. Epub 2014 Aug 25. ACS Chem Neurosci. 2014. PMID: 25123416 Free PMC article.
The emerging role of lysine methyltransferase SETD8 in human diseases.
Milite C, Feoli A, Viviano M, Rescigno D, Cianciulli A, Balzano AL, Mai A, Castellano S, Sbardella G. Milite C, et al. Among authors: castellano s. Clin Epigenetics. 2016 Sep 22;8:102. doi: 10.1186/s13148-016-0268-4. eCollection 2016. Clin Epigenetics. 2016. PMID: 27688818 Free PMC article. Review.
249 results