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Successful use of casirivimab/imdevimab anti-spike monoclonal antibodies to enhance neutralizing antibodies in a woman on anti-CD20 treatment with refractory COVID-19.
Miyazato Y, Yamamoto K, Nakaya Y, Morioka S, Takeuchi JS, Takamatsu Y, Maeda K, Kimura M, Sugiura W, Mitsuya H, Yano M, Ohmagari N. Miyazato Y, et al. Among authors: takamatsu y. J Infect Chemother. 2022 Jul;28(7):991-994. doi: 10.1016/j.jiac.2022.03.002. Epub 2022 Mar 23. J Infect Chemother. 2022. PMID: 35337728 Free PMC article.
GRL-079, a Novel HIV-1 Protease Inhibitor, Is Extremely Potent against Multidrug-Resistant HIV-1 Variants and Has a High Genetic Barrier against the Emergence of Resistant Variants.
Delino NS, Aoki M, Hayashi H, Hattori SI, Chang SB, Takamatsu Y, Martyr CD, Das D, Ghosh AK, Mitsuya H. Delino NS, et al. Among authors: takamatsu y. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02060-17. doi: 10.1128/AAC.02060-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463535 Free PMC article.
Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2' Ligands That Exert Potent Antiviral Activity against Highly Multidrug-Resistant HIV-1 with a High Genetic Barrier against the Emergence of Drug Resistance.
Takamatsu Y, Aoki M, Bulut H, Das D, Amano M, Sheri VR, Kovari LC, Hayashi H, Delino NS, Ghosh AK, Mitsuya H. Takamatsu Y, et al. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00372-19. doi: 10.1128/AAC.00372-19. Print 2019 Aug. Antimicrob Agents Chemother. 2019. PMID: 31085520 Free PMC article.
Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-Ligand X-ray Structural Studies.
Ghosh AK, Xia Z, Kovela S, Robinson WL, Johnson ME, Kneller DW, Wang YF, Aoki M, Takamatsu Y, Weber IT, Mitsuya H. Ghosh AK, et al. Among authors: takamatsu y. ChemMedChem. 2019 Nov 6;14(21):1863-1872. doi: 10.1002/cmdc.201900508. Epub 2019 Oct 4. ChemMedChem. 2019. PMID: 31549492 Free PMC article.
A familial cluster of severe coronavirus disease 2019 that required intubation of all family members.
Katsuno T, Suzuki M, Ishikane M, Kinoshita N, Tsukada A, Morita C, Kusaba Y, Sakamoto K, Yamaguchi Y, Tsujimoto Y, Hashimoto M, Terada J, Takasaki J, Izumi S, Okuhama A, Ide S, Moriyama Y, Matsuda K, Takamatsu Y, Mitsuya H, Hojo M, Sugiyama H. Katsuno T, et al. Among authors: takamatsu y. Infect Dis (Lond). 2020 Oct;52(10):755-758. doi: 10.1080/23744235.2020.1784999. Epub 2020 Jul 2. Infect Dis (Lond). 2020. PMID: 32615051 No abstract available.
GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection.
Hattori SI, Higshi-Kuwata N, Raghavaiah J, Das D, Bulut H, Davis DA, Takamatsu Y, Matsuda K, Takamune N, Kishimoto N, Okamura T, Misumi S, Yarchoan R, Maeda K, Ghosh AK, Mitsuya H. Hattori SI, et al. Among authors: takamatsu y. mBio. 2020 Aug 20;11(4):e01833-20. doi: 10.1128/mBio.01833-20. mBio. 2020. PMID: 32820005 Free PMC article.
496 results