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BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells.
Moujalled D, Southon AG, Saleh E, Brinkmann K, Ke F, Iliopoulos M, Cross RS, Jenkins MR, Nhu D, Wang Z, Shi MX, Kluck RM, Lessene G, Grabow S, Bush AI, Strasser A. Moujalled D, et al. Among authors: bush ai. Cell Death Differ. 2022 Jul;29(7):1335-1348. doi: 10.1038/s41418-022-00977-2. Epub 2022 Mar 24. Cell Death Differ. 2022. PMID: 35332309 Free PMC article.
Presenilin promotes dietary copper uptake.
Southon A, Greenough MA, Ganio G, Bush AI, Burke R, Camakaris J. Southon A, et al. Among authors: bush ai. PLoS One. 2013 May 7;8(5):e62811. doi: 10.1371/journal.pone.0062811. Print 2013. PLoS One. 2013. PMID: 23667524 Free PMC article.
Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin.
Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT. Venkataramani V, et al. Among authors: bush ai. J Neurochem. 2018 Dec;147(6):831-848. doi: 10.1111/jnc.14580. Epub 2018 Nov 19. J Neurochem. 2018. PMID: 30152072 Free PMC article.
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis.
Wang T, Tomas D, Perera ND, Cuic B, Luikinga S, Viden A, Barton SK, McLean CA, Samson AL, Southon A, Bush AI, Murphy JM, Turner BJ. Wang T, et al. Among authors: bush ai. Cell Death Differ. 2022 Jun;29(6):1187-1198. doi: 10.1038/s41418-021-00910-z. Epub 2021 Dec 2. Cell Death Differ. 2022. PMID: 34857917 Free PMC article.
Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging.
Leiter O, Zhuo Z, Rust R, Wasielewska JM, Grönnert L, Kowal S, Overall RW, Adusumilli VS, Blackmore DG, Southon A, Ganio K, McDevitt CA, Rund N, Brici D, Mudiyan IA, Sykes AM, Rünker AE, Zocher S, Ayton S, Bush AI, Bartlett PF, Hou ST, Kempermann G, Walker TL. Leiter O, et al. Among authors: bush ai. Cell Metab. 2022 Mar 1;34(3):408-423.e8. doi: 10.1016/j.cmet.2022.01.005. Epub 2022 Feb 3. Cell Metab. 2022. PMID: 35120590 Free article.
Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations.
Greenough MA, Lane DJR, Balez R, Anastacio HTD, Zeng Z, Ganio K, McDevitt CA, Acevedo K, Belaidi AA, Koistinaho J, Ooi L, Ayton S, Bush AI. Greenough MA, et al. Among authors: bush ai. Cell Death Differ. 2022 Nov;29(11):2123-2136. doi: 10.1038/s41418-022-01003-1. Epub 2022 Apr 21. Cell Death Differ. 2022. PMID: 35449212 Free PMC article.
Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy.
Belaidi AA, Masaldan S, Southon A, Kalinowski P, Acevedo K, Appukuttan AT, Portbury S, Lei P, Agarwal P, Leurgans SE, Schneider J, Conrad M, Bush AI, Ayton S. Belaidi AA, et al. Among authors: bush ai. Mol Psychiatry. 2024 Feb;29(2):211-220. doi: 10.1038/s41380-022-01568-w. Epub 2022 Apr 28. Mol Psychiatry. 2024. PMID: 35484240 Free PMC article.
489 results