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AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
Raake PW, Schlegel P, Ksienzyk J, Reinkober J, Barthelmes J, Schinkel S, Pleger S, Mier W, Haberkorn U, Koch WJ, Katus HA, Most P, Müller OJ. Raake PW, et al. Among authors: schlegel p. Eur Heart J. 2013 May;34(19):1437-47. doi: 10.1093/eurheartj/ehr447. Epub 2012 Jan 19. Eur Heart J. 2013. PMID: 22261894 Free PMC article.
G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.
Schlegel P, Reinkober J, Meinhardt E, Tscheschner H, Gao E, Schumacher SM, Yuan A, Backs J, Most P, Wieland T, Koch WJ, Katus HA, Raake PW. Schlegel P, et al. PLoS One. 2017 Jul 31;12(7):e0182110. doi: 10.1371/journal.pone.0182110. eCollection 2017. PLoS One. 2017. PMID: 28759639 Free PMC article.
Comprehensive cardiac phenotyping in large animals: comparison of pressure-volume analysis and cardiac magnetic resonance imaging in pig post-myocardial infarction systolic heart failure.
Raake PWJ, Barthelmes J, Krautz B, Buss S, Huditz R, Schlegel P, Weber C, Stangassinger M, Haberkorn U, Katus HA, Most P, Pleger ST. Raake PWJ, et al. Among authors: schlegel p. Int J Cardiovasc Imaging. 2019 Sep;35(9):1691-1699. doi: 10.1007/s10554-019-01610-z. Epub 2019 May 5. Int J Cardiovasc Imaging. 2019. PMID: 31056718
744 results