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A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial.
Hasenfuß G, Hayward C, Burkhoff D, Silvestry FE, McKenzie S, Gustafsson F, Malek F, Van der Heyden J, Lang I, Petrie MC, Cleland JG, Leon M, Kaye DM; REDUCE LAP-HF study investigators. Hasenfuß G, et al. Lancet. 2016 Mar 26;387(10025):1298-304. doi: 10.1016/S0140-6736(16)00704-2. Lancet. 2016. PMID: 27025436 Free article. Clinical Trial.
Gene therapy targets in heart failure: the path to translation.
Raake PW, Tscheschner H, Reinkober J, Ritterhoff J, Katus HA, Koch WJ, Most P. Raake PW, et al. Clin Pharmacol Ther. 2011 Oct;90(4):542-53. doi: 10.1038/clpt.2011.148. Epub 2011 Aug 24. Clin Pharmacol Ther. 2011. PMID: 21866097 Free PMC article. Review.
AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
Raake PW, Schlegel P, Ksienzyk J, Reinkober J, Barthelmes J, Schinkel S, Pleger S, Mier W, Haberkorn U, Koch WJ, Katus HA, Most P, Müller OJ. Raake PW, et al. Eur Heart J. 2013 May;34(19):1437-47. doi: 10.1093/eurheartj/ehr447. Epub 2012 Jan 19. Eur Heart J. 2013. PMID: 22261894 Free PMC article.
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW 2nd, Houser SR, Katus HA, Chen X, Koch WJ. Raake PW, et al. Circulation. 2012 May 1;125(17):2108-18. doi: 10.1161/CIRCULATIONAHA.111.044255. Epub 2012 Apr 10. Circulation. 2012. PMID: 22496128 Free PMC article.
S100A1 gene therapy in small and large animals.
Most P, Raake P, Weber C, Katus HA, Pleger ST. Most P, et al. Methods Mol Biol. 2013;963:407-20. doi: 10.1007/978-1-62703-230-8_25. Methods Mol Biol. 2013. PMID: 23296625
96 results