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Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis.
Claesen K, Sim Y, Bracke A, De Bruyn M, De Hert E, Vliegen G, Hotterbeekx A, Vujkovic A, van Petersen L, De Winter FHR, Brosius I, Theunissen C, van Ierssel S, van Frankenhuijsen M, Vlieghe E, Vercauteren K, Kumar-Singh S, De Meester I, Hendriks D. Claesen K, et al. Among authors: de hert e. J Clin Med. 2022 Mar 9;11(6):1494. doi: 10.3390/jcm11061494. J Clin Med. 2022. PMID: 35329820 Free PMC article.
DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
de Vasconcelos NM, Vliegen G, Gonçalves A, De Hert E, Martín-Pérez R, Van Opdenbosch N, Jallapally A, Geiss-Friedlander R, Lambeir AM, Augustyns K, Van Der Veken P, De Meester I, Lamkanfi M. de Vasconcelos NM, et al. Among authors: de hert e. Life Sci Alliance. 2019 Feb 4;2(1):e201900313. doi: 10.26508/lsa.201900313. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30718379 Free PMC article.
Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2).
Vliegen G, Kehoe K, Bracke A, De Hert E, Verkerk R, Fransen E, Jongers B', Peters E, Lambeir AM, Kumar-Singh S, Pickkers P, Jorens PG, De Meester I. Vliegen G, et al. Among authors: de hert e. PLoS One. 2020 Apr 21;15(4):e0231555. doi: 10.1371/journal.pone.0231555. eCollection 2020. PLoS One. 2020. PMID: 32315321 Free PMC article.
Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patients.
Bracke A, De Hert E, De Bruyn M, Claesen K, Vliegen G, Vujkovic A, van Petersen L, De Winter FHR, Hotterbeekx A, Brosius I, Theunissen C, Van Ierssel S, van Frankenhuijsen M, Vlieghe E, Vercauteren K, Van der Veken P, Hendriks D, Kumar-Singh S, De Meester I. Bracke A, et al. Among authors: de hert e. Clin Chim Acta. 2022 Jun 1;531:4-11. doi: 10.1016/j.cca.2022.03.005. Epub 2022 Mar 10. Clin Chim Acta. 2022. PMID: 35283094 Free PMC article.