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2-Aminoimidazoles Inhibit Mycobacterium abscessus Biofilms in a Zinc-Dependent Manner.
Belardinelli JM, Li W, Martin KH, Zeiler MJ, Lian E, Avanzi C, Wiersma CJ, Nguyen TV, Angala B, de Moura VCN, Jones V, Borlee BR, Melander C, Jackson M. Belardinelli JM, et al. Among authors: jackson m. Int J Mol Sci. 2022 Mar 9;23(6):2950. doi: 10.3390/ijms23062950. Int J Mol Sci. 2022. PMID: 35328372 Free PMC article.
Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.
Grzegorzewicz AE, Pham H, Gundi VA, Scherman MS, North EJ, Hess T, Jones V, Gruppo V, Born SE, Korduláková J, Chavadi SS, Morisseau C, Lenaerts AJ, Lee RE, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: jackson m. Nat Chem Biol. 2012 Feb 19;8(4):334-41. doi: 10.1038/nchembio.794. Nat Chem Biol. 2012. PMID: 22344175 Free PMC article.
Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.
Scherman MS, North EJ, Jones V, Hess TN, Grzegorzewicz AE, Kasagami T, Kim IH, Merzlikin O, Lenaerts AJ, Lee RE, Jackson M, Morisseau C, McNeil MR. Scherman MS, et al. Among authors: jackson m. Bioorg Med Chem. 2012 May 15;20(10):3255-62. doi: 10.1016/j.bmc.2012.03.058. Epub 2012 Mar 31. Bioorg Med Chem. 2012. PMID: 22522007 Free PMC article.
A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: jackson m. J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21. J Biol Chem. 2012. PMID: 23002234 Free PMC article.
The cell envelope glycoconjugates of Mycobacterium tuberculosis.
Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M. Angala SK, et al. Among authors: jackson m. Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Crit Rev Biochem Mol Biol. 2014. PMID: 24915502 Free PMC article. Review.
Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis.
Li W, Upadhyay A, Fontes FL, North EJ, Wang Y, Crans DC, Grzegorzewicz AE, Jones V, Franzblau SG, Lee RE, Crick DC, Jackson M. Li W, et al. Among authors: jackson m. Antimicrob Agents Chemother. 2014 Nov;58(11):6413-23. doi: 10.1128/AAC.03229-14. Epub 2014 Aug 18. Antimicrob Agents Chemother. 2014. PMID: 25136022 Free PMC article.
5,044 results