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Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo.
Biomolecules. 2022 Mar 18;12(3):469. doi: 10.3390/biom12030469.
Biomolecules. 2022.
PMID: 35327661
Free PMC article.
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils.
Agerschou ED, Flagmeier P, Saridaki T, Galvagnion C, Komnig D, Heid L, Prasad V, Shaykhalishahi H, Willbold D, Dobson CM, Voigt A, Falkenburger B, Hoyer W, Buell AK.
Agerschou ED, et al.
Elife. 2019 Aug 21;8:e46112. doi: 10.7554/eLife.46112.
Elife. 2019.
PMID: 31389332
Free PMC article.
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β-Turn exchanges in the α-synuclein segment 44-TKEG-47 reveal high sequence fidelity requirements of amyloid fibril elongation.
Agerschou ED, Schützmann MP, Reppert N, Wördehoff MM, Shaykhalishahi H, Buell AK, Hoyer W.
Agerschou ED, et al.
Biophys Chem. 2021 Feb;269:106519. doi: 10.1016/j.bpc.2020.106519. Epub 2020 Dec 5.
Biophys Chem. 2021.
PMID: 33333378
Free article.
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Inhibitor and substrate cooperate to inhibit amyloid fibril elongation of α-synuclein.
Agerschou ED, Borgmann V, Wördehoff MM, Hoyer W.
Agerschou ED, et al.
Chem Sci. 2020 Sep 28;11(41):11331-11337. doi: 10.1039/d0sc04051g.
Chem Sci. 2020.
PMID: 34094375
Free PMC article.
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The transcriptional regulator GalR self-assembles to form highly regular tubular structures.
Agerschou ED, Christiansen G, Schafer NP, Madsen DJ, Brodersen DE, Semsey S, Otzen DE.
Agerschou ED, et al.
Sci Rep. 2016 Jun 9;6:27672. doi: 10.1038/srep27672.
Sci Rep. 2016.
PMID: 27279285
Free PMC article.
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Structural characterization of the Saccharomyces cerevisiae THO complex by small-angle X-ray scattering.
Poulsen JB, Sanderson LE, Agerschou ED, Dedic E, Boesen T, Brodersen DE.
Poulsen JB, et al. Among authors: agerschou ed.
PLoS One. 2014 Jul 25;9(7):e103470. doi: 10.1371/journal.pone.0103470. eCollection 2014.
PLoS One. 2014.
PMID: 25062267
Free PMC article.
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Sequence-based identification of amyloidogenic β-hairpins reveals a prostatic acid phosphatase fragment promoting semen amyloid formation.
Heid LF, Agerschou ED, Orr AA, Kupreichyk T, Schneider W, Wördehoff MM, Schwarten M, Willbold D, Tamamis P, Stoldt M, Hoyer W.
Heid LF, et al. Among authors: agerschou ed.
Comput Struct Biotechnol J. 2023 Dec 21;23:417-430. doi: 10.1016/j.csbj.2023.12.023. eCollection 2024 Dec.
Comput Struct Biotechnol J. 2023.
PMID: 38223341
Free PMC article.
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