Ferguson EL - Search Results

1

Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment.

Stokniene J, Varache M, Rye PD, Hill KE, Thomas DW, Ferguson EL. Stokniene J, et al. Among authors: ferguson el. Sci Rep. 2022 Mar 23;12(1):4986. doi: 10.1038/s41598-022-08927-1. Sci Rep. 2022. PMID: 35322119 Free PMC article.

2

The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption.

Pritchard MF, Powell LC, Khan S, Griffiths PC, Mansour OT, Schweins R, Beck K, Buurma NJ, Dempsey CE, Wright CJ, Rye PD, Hill KE, Thomas DW, Ferguson EL. Pritchard MF, et al. Among authors: ferguson el. Sci Rep. 2017 Mar 31;7:44731. doi: 10.1038/srep44731. Sci Rep. 2017. PMID: 28361894 Free PMC article.

3

Polymer Masked-Unmasked Protein Therapy: Identification of the Active Species after Amylase Activation of Dextrin-Colistin Conjugates.

Varache M, Powell LC, Aarstad OA, Williams TL, Wenzel MN, Thomas DW, Ferguson EL. Varache M, et al. Among authors: ferguson el. Mol Pharm. 2019 Jul 1;16(7):3199-3207. doi: 10.1021/acs.molpharmaceut.9b00393. Epub 2019 Jun 5. Mol Pharm. 2019. PMID: 31125239 Free PMC article.

4

A physicochemical assessment of the thermal stability of dextrin-colistin conjugates.

Chiron E, Varache M, Stokniene J, Thomas DW, Ferguson EL. Chiron E, et al. Among authors: ferguson el. Sci Rep. 2021 May 19;11(1):10600. doi: 10.1038/s41598-021-89946-2. Sci Rep. 2021. PMID: 34011987 Free PMC article.

5

Colistin past and future: a bibliographic analysis.

Azzopardi EA, Ferguson EL, Thomas DW. Azzopardi EA, et al. Among authors: ferguson el. J Crit Care. 2013 Apr;28(2):219.e13-9. doi: 10.1016/j.jcrc.2012.04.008. Epub 2012 Jul 2. J Crit Care. 2013. PMID: 22762926

6

Dextrin-colistin conjugates as a model bioresponsive treatment for multidrug resistant bacterial infections.

Ferguson EL, Azzopardi E, Roberts JL, Walsh TR, Thomas DW. Ferguson EL, et al. Mol Pharm. 2014 Dec 1;11(12):4437-47. doi: 10.1021/mp500584u. Epub 2014 Nov 17. Mol Pharm. 2014. PMID: 25360900

7

Development and validation of an in vitro pharmacokinetic/pharmacodynamic model to test the antibacterial efficacy of antibiotic polymer conjugates.

Azzopardi EA, Ferguson EL, Thomas DW. Azzopardi EA, et al. Among authors: ferguson el. Antimicrob Agents Chemother. 2015 Apr;59(4):1837-43. doi: 10.1128/AAC.03708-14. Epub 2014 Dec 15. Antimicrob Agents Chemother. 2015. PMID: 25512401 Free PMC article.

8

Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides.

Powell LC, Pritchard MF, Ferguson EL, Powell KA, Patel SU, Rye PD, Sakellakou SM, Buurma NJ, Brilliant CD, Copping JM, Menzies GE, Lewis PD, Hill KE, Thomas DW. Powell LC, et al. Among authors: ferguson el. NPJ Biofilms Microbiomes. 2018 Jun 29;4:13. doi: 10.1038/s41522-018-0056-3. eCollection 2018. NPJ Biofilms Microbiomes. 2018. PMID: 29977590 Free PMC article.

9

Bi-Functional Alginate Oligosaccharide-Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections.

Stokniene J, Powell LC, Aarstad OA, Aachmann FL, Rye PD, Hill KE, Thomas DW, Ferguson EL. Stokniene J, et al. Among authors: ferguson el. Pharmaceutics. 2020 Nov 11;12(11):1080. doi: 10.3390/pharmaceutics12111080. Pharmaceutics. 2020. PMID: 33187332 Free PMC article.

10

The enhanced permeability retention effect: a new paradigm for drug targeting in infection.

Azzopardi EA, Ferguson EL, Thomas DW. Azzopardi EA, et al. Among authors: ferguson el. J Antimicrob Chemother. 2013 Feb;68(2):257-74. doi: 10.1093/jac/dks379. Epub 2012 Oct 10. J Antimicrob Chemother. 2013. PMID: 23054997 Review.

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