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XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.
Lee K, Chan JY, Liang C, Ip CK, Shi YC, Herzog H, Hughes WE, Bensellam M, Delghingaro-Augusto V, Koina ME, Nolan CJ, Laybutt DR. Lee K, et al. Among authors: herzog h. Diabetologia. 2022 Jun;65(6):984-996. doi: 10.1007/s00125-022-05669-7. Epub 2022 Mar 22. Diabetologia. 2022. PMID: 35316840 Free PMC article.
Inhibition of Y1 receptor signaling improves islet transplant outcome.
Loh K, Shi YC, Walters S, Bensellam M, Lee K, Dezaki K, Nakata M, Ip CK, Chan JY, Gurzov EN, Thomas HE, Waibel M, Cantley J, Kay TW, Yada T, Laybutt DR, Grey ST, Herzog H. Loh K, et al. Among authors: herzog h. Nat Commun. 2017 Sep 8;8(1):490. doi: 10.1038/s41467-017-00624-2. Nat Commun. 2017. PMID: 28887564 Free PMC article.
Chronic stress and energy homoeostasis.
Ip CK, Herzog H, Zhang L. Ip CK, et al. Among authors: herzog h. Aging (Albany NY). 2019 Nov 20;11(22):9963-9964. doi: 10.18632/aging.102500. Epub 2019 Nov 20. Aging (Albany NY). 2019. PMID: 31754083 Free PMC article. No abstract available.
Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes.
Yang CH, Ann-Onda D, Lin X, Fynch S, Nadarajah S, Pappas EG, Liu X, Scott JW, Oakhill JS, Galic S, Shi Y, Moreno-Asso A, Smith C, Loudovaris T, Levinger I, Eizirik DL, Laybutt DR, Herzog H, Thomas HE, Loh K. Yang CH, et al. Among authors: herzog h. Mol Metab. 2022 Jan;55:101413. doi: 10.1016/j.molmet.2021.101413. Epub 2021 Dec 7. Mol Metab. 2022. PMID: 34890851 Free PMC article.
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity.
Yan C, Zeng T, Lee K, Nobis M, Loh K, Gou L, Xia Z, Gao Z, Bensellam M, Hughes W, Lau J, Zhang L, Ip CK, Enriquez R, Gao H, Wang QP, Wu Q, Haigh JJ, Laybutt DR, Timpson P, Herzog H, Shi YC. Yan C, et al. Among authors: herzog h. Nat Commun. 2021 May 11;12(1):2622. doi: 10.1038/s41467-021-22925-3. Nat Commun. 2021. PMID: 33976180 Free PMC article.
Regulation of energy homeostasis by the NPY system.
Loh K, Herzog H, Shi YC. Loh K, et al. Among authors: herzog h. Trends Endocrinol Metab. 2015 Mar;26(3):125-35. doi: 10.1016/j.tem.2015.01.003. Epub 2015 Feb 5. Trends Endocrinol Metab. 2015. PMID: 25662369 Review.
798 results