Yaffe MB - Search Results

1

An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils.

Ellson CD, Riça IG, Kim JS, Huang YM, Lim D, Mitra T, Hsu A, Wei EX, Barrett CD, Otterbein LE, Hauser CJ, Wahl M, Delbrück H, Heinemann U, Oschkinat H, Chang CA, Yaffe MB. Ellson CD, et al. Among authors: yaffe mb. J Mol Biol. 2022 May 15;434(9):167533. doi: 10.1016/j.jmb.2022.167533. Epub 2022 Mar 18. J Mol Biol. 2022. PMID: 35314146

2

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K.

Kanai F, Liu H, Field SJ, Akbary H, Matsuo T, Brown GE, Cantley LC, Yaffe MB. Kanai F, et al. Among authors: yaffe mb. Nat Cell Biol. 2001 Jul;3(7):675-8. doi: 10.1038/35083070. Nat Cell Biol. 2001. PMID: 11433300

3

A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase.

Brown GE, Stewart MQ, Liu H, Ha VL, Yaffe MB. Brown GE, et al. Among authors: yaffe mb. Mol Cell. 2003 Jan;11(1):35-47. doi: 10.1016/s1097-2765(03)00005-4. Mol Cell. 2003. PMID: 12535519 Free article.

4

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.

Manke IA, Nguyen A, Lim D, Stewart MQ, Elia AE, Yaffe MB. Manke IA, et al. Among authors: yaffe mb. Mol Cell. 2005 Jan 7;17(1):37-48. doi: 10.1016/j.molcel.2004.11.021. Mol Cell. 2005. PMID: 15629715 Free article.

5

Structure and function of Polo-like kinases.

Lowery DM, Lim D, Yaffe MB. Lowery DM, et al. Among authors: yaffe mb. Oncogene. 2005 Jan 10;24(2):248-59. doi: 10.1038/sj.onc.1208280. Oncogene. 2005. PMID: 15640840 Review.

6

The antiproliferative cytostatic effects of a self-activating viridin prodrug.

Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L. Smith A, et al. Among authors: yaffe mb. Mol Cancer Ther. 2009 Jun;8(6):1666-75. doi: 10.1158/1535-7163.MCT-08-1012. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509266 Free PMC article.

7

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, Smerdon SJ, Yaffe MB. Alexander J, et al. Among authors: yaffe mb. Sci Signal. 2011 Jun 28;4(179):ra42. doi: 10.1126/scisignal.2001796. Sci Signal. 2011. PMID: 21712545 Free PMC article.

8

Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress.

Tentner AR, Lee MJ, Ostheimer GJ, Samson LD, Lauffenburger DA, Yaffe MB. Tentner AR, et al. Among authors: yaffe mb. Mol Syst Biol. 2012 Jan 31;8:568. doi: 10.1038/msb.2012.1. Mol Syst Biol. 2012. PMID: 22294094 Free PMC article.

9

Exploiting synthetic lethal interactions between DNA damage signaling, checkpoint control, and p53 for targeted cancer therapy.

Morandell S, Yaffe MB. Morandell S, et al. Among authors: yaffe mb. Prog Mol Biol Transl Sci. 2012;110:289-314. doi: 10.1016/B978-0-12-387665-2.00011-0. Prog Mol Biol Transl Sci. 2012. PMID: 22749150 Review.

10

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

Niedelman W, Gold DA, Rosowski EE, Sprokholt JK, Lim D, Farid Arenas A, Melo MB, Spooner E, Yaffe MB, Saeij JP. Niedelman W, et al. Among authors: yaffe mb. PLoS Pathog. 2012;8(6):e1002784. doi: 10.1371/journal.ppat.1002784. Epub 2012 Jun 28. PLoS Pathog. 2012. PMID: 22761577 Free PMC article.

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