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An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils.
Ellson CD, Riça IG, Kim JS, Huang YM, Lim D, Mitra T, Hsu A, Wei EX, Barrett CD, Otterbein LE, Hauser CJ, Wahl M, Delbrück H, Heinemann U, Oschkinat H, Chang CA, Yaffe MB. Ellson CD, et al. Among authors: otterbein le. J Mol Biol. 2022 May 15;434(9):167533. doi: 10.1016/j.jmb.2022.167533. Epub 2022 Mar 18. J Mol Biol. 2022. PMID: 35314146
Heme oxygenase and carbon monoxide initiate homeostatic signaling.
Bilban M, Haschemi A, Wegiel B, Chin BY, Wagner O, Otterbein LE. Bilban M, et al. Among authors: otterbein le. J Mol Med (Berl). 2008 Mar;86(3):267-79. doi: 10.1007/s00109-007-0276-0. Epub 2007 Nov 22. J Mol Med (Berl). 2008. PMID: 18034222 Review.
Mitochondrial DNA released by trauma induces neutrophil extracellular traps.
Itagaki K, Kaczmarek E, Lee YT, Tang IT, Isal B, Adibnia Y, Sandler N, Grimm MJ, Segal BH, Otterbein LE, Hauser CJ. Itagaki K, et al. Among authors: otterbein le. PLoS One. 2015 Mar 16;10(3):e0120549. doi: 10.1371/journal.pone.0120549. eCollection 2015. PLoS One. 2015. PMID: 25774524 Free PMC article.
Heme as a danger molecule in pathogen recognition.
Wegiel B, Hauser CJ, Otterbein LE. Wegiel B, et al. Among authors: otterbein le. Free Radic Biol Med. 2015 Dec;89:651-61. doi: 10.1016/j.freeradbiomed.2015.08.020. Epub 2015 Oct 9. Free Radic Biol Med. 2015. PMID: 26456060 Review.
Carbon monoxide protects the kidney through the central circadian clock and CD39.
Correa-Costa M, Gallo D, Csizmadia E, Gomperts E, Lieberum JL, Hauser CJ, Ji X, Wang B, Câmara NOS, Robson SC, Otterbein LE. Correa-Costa M, et al. Among authors: otterbein le. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2302-E2310. doi: 10.1073/pnas.1716747115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463714 Free PMC article.
188 results