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Rethinking chronic toxicity and carcinogenicity assessment for agrochemicals project (ReCAAP): A reporting framework to support a weight of evidence safety assessment without long-term rodent bioassays.
Hilton GM, Adcock C, Akerman G, Baldassari J, Battalora M, Casey W, Clippinger AJ, Cope R, Goetz A, Hayes AW, Papineni S, Peffer RC, Ramsingh D, Williamson Riffle B, Sanches da Rocha M, Ryan N, Scollon E, Visconti N, Wolf DC, Yan Z, Lowit A. Hilton GM, et al. Among authors: lowit a. Regul Toxicol Pharmacol. 2022 Jun;131:105160. doi: 10.1016/j.yrtph.2022.105160. Epub 2022 Mar 17. Regul Toxicol Pharmacol. 2022. PMID: 35311659 Free article.
Workshop overview: arsenic research and risk assessment.
Sams R 2nd, Wolf DC, Ramasamy S, Ohanian E, Chen J, Lowit A. Sams R 2nd, et al. Among authors: lowit a. Toxicol Appl Pharmacol. 2007 Aug 1;222(3):245-51. doi: 10.1016/j.taap.2007.01.007. Epub 2007 Jan 20. Toxicol Appl Pharmacol. 2007. PMID: 17336359
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: lowit a. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: lowit a. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.
Casati S, Aschberger K, Barroso J, Casey W, Delgado I, Kim TS, Kleinstreuer N, Kojima H, Lee JK, Lowit A, Park HK, Régimbald-Krnel MJ, Strickland J, Whelan M, Yang Y, Zuang V. Casati S, et al. Among authors: lowit a. Arch Toxicol. 2018 Feb;92(2):611-617. doi: 10.1007/s00204-017-2097-4. Epub 2017 Nov 10. Arch Toxicol. 2018. PMID: 29127450 Free PMC article.
Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.
Clippinger AJ, Allen D, Jarabek AM, Corvaro M, Gaça M, Gehen S, Hotchkiss JA, Patlewicz G, Melbourne J, Hinderliter P, Yoon M, Huh D, Lowit A, Buckley B, Bartels M, BéruBé K, Wilson DM, Indans I, Vinken M. Clippinger AJ, et al. Among authors: lowit a. Toxicol In Vitro. 2018 Apr;48:53-70. doi: 10.1016/j.tiv.2017.12.011. Epub 2017 Dec 22. Toxicol In Vitro. 2018. PMID: 29277654 Free PMC article.
Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies.
Strickland J, Clippinger AJ, Brown J, Allen D, Jacobs A, Matheson J, Lowit A, Reinke EN, Johnson MS, Quinn MJ Jr, Mattie D, Fitzpatrick SC, Ahir S, Kleinstreuer N, Casey W. Strickland J, et al. Among authors: lowit a. Regul Toxicol Pharmacol. 2018 Apr;94:183-196. doi: 10.1016/j.yrtph.2018.01.022. Epub 2018 Feb 3. Regul Toxicol Pharmacol. 2018. PMID: 29408321 Free PMC article. Review.
69 results