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Translating pharmacology models effectively to predict therapeutic benefit.
Dudal S, Bissantz C, Caruso A, David-Pierson P, Driessen W, Koller E, Krippendorff BF, Lechmann M, Olivares-Morales A, Paehler A, Rynn C, Türck D, Van De Vyver A, Wang K, Winther L. Dudal S, et al. Among authors: wang k. Drug Discov Today. 2022 Jun;27(6):1604-1621. doi: 10.1016/j.drudis.2022.03.009. Epub 2022 Mar 15. Drug Discov Today. 2022. PMID: 35304340 Free article. Review.
Multiscale modelling of drug mechanism and safety.
Zhang JD, Sach-Peltason L, Kramer C, Wang K, Ebeling M. Zhang JD, et al. Among authors: wang k. Drug Discov Today. 2020 Mar;25(3):519-534. doi: 10.1016/j.drudis.2019.12.009. Epub 2019 Dec 30. Drug Discov Today. 2020. PMID: 31899257 Free article. Review.
Perspectives of data science in preclinical safety assessment.
Steger-Hartmann T, Kreuchwig A, Wang K, Birzele F, Draganov D, Gaudio S, Rothfuss A. Steger-Hartmann T, et al. Among authors: wang k. Drug Discov Today. 2023 Aug;28(8):103642. doi: 10.1016/j.drudis.2023.103642. Epub 2023 May 26. Drug Discov Today. 2023. PMID: 37244565 Review.
Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.
Lei CL, Clerx M, Beattie KA, Melgari D, Hancox JC, Gavaghan DJ, Polonchuk L, Wang K, Mirams GR. Lei CL, et al. Among authors: wang k. Biophys J. 2019 Dec 17;117(12):2455-2470. doi: 10.1016/j.bpj.2019.07.030. Epub 2019 Jul 25. Biophys J. 2019. PMID: 31451180 Free PMC article.
Models of the cardiac L-type calcium current: A quantitative review.
Agrawal A, Wang K, Polonchuk L, Cooper J, Hendrix M, Gavaghan DJ, Mirams GR, Clerx M. Agrawal A, et al. Among authors: wang k. WIREs Mech Dis. 2023 Jan;15(1):e1581. doi: 10.1002/wsbm.1581. Epub 2022 Aug 26. WIREs Mech Dis. 2023. PMID: 36028219 Free PMC article. Review.
37,212 results
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