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Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission.
J Allergy Clin Immunol. 2022 Jun;149(6):2062-2077. doi: 10.1016/j.jaci.2022.02.025. Epub 2022 Mar 15.
J Allergy Clin Immunol. 2022.
PMID: 35304158
Free PMC article.
Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes.
Kottyan LC, Trimarchi MP, Lu X, Caldwell JM, Maddox A, Parameswaran S, Lape M, D'Mello RJ, Bonfield M, Ballaban A, Mukkada V, Putnam PE, Abonia P, Ben-Baruch Morgenstern N, Eapen AA, Wen T, Weirauch MT, Rothenberg ME.
Kottyan LC, et al.
J Allergy Clin Immunol. 2021 Jan;147(1):255-266. doi: 10.1016/j.jaci.2020.10.018. Epub 2020 Oct 23.
J Allergy Clin Immunol. 2021.
PMID: 33446330
Free PMC article.
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Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes.
Dunn JLM, Caldwell JM, Ballaban A, Ben-Baruch Morgenstern N, Rochman M, Rothenberg ME.
Dunn JLM, et al.
Mucosal Immunol. 2021 Sep;14(5):1133-1143. doi: 10.1038/s41385-021-00400-y. Epub 2021 May 10.
Mucosal Immunol. 2021.
PMID: 33972688
Free PMC article.
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Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis.
Shoda T, Kaufman KM, Wen T, Caldwell JM, Osswald GA, Purnima P, Zimmermann N, Collins MH, Rehn K, Foote H, Eby MD, Zhang W, Ben-Baruch Morgenstern N, Ballaban AY, Habel JE, Kottyan LC, Abonia JP, Mukkada VA, Putnam PE, Martin LJ, Rothenberg ME.
Shoda T, et al. Among authors: ballaban ay.
Nat Commun. 2021 Nov 23;12(1):6795. doi: 10.1038/s41467-021-26939-9.
Nat Commun. 2021.
PMID: 34815391
Free PMC article.
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Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis.
Avlas S, Shani G, Rhone N, Itan M, Dolitzky A, Hazut I, Grisaru-Tal S, Gordon Y, Shoda T, Ballaban A, Ben-Baruch NM, Rochman M, Diesendruck Y, Nahary L, Bitton A, Halpern Z, Benhar I, Varol C, Rothenberg ME, Munitz A.
Avlas S, et al.
Allergy. 2023 Feb;78(2):464-476. doi: 10.1111/all.15510. Epub 2022 Sep 13.
Allergy. 2023.
PMID: 36070083
Free PMC article.
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Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis.
Azouz NP, Klingler AM, Pathre P, Besse JA, Baruch-Morgenstern NB, Ballaban AY, Osswald GA, Brusilovsky M, Habel JE, Caldwell JM, Ynga-Durand MA, Abonia PJ, Hu YC, Wen T, Rothenberg ME.
Azouz NP, et al. Among authors: ballaban ay.
Sci Transl Med. 2020 May 27;12(545):eaaz7773. doi: 10.1126/scitranslmed.aaz7773.
Sci Transl Med. 2020.
PMID: 32461336
Free PMC article.
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