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Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes.
Gkogkas CG, Khoutorsky A, Cao R, Jafarnejad SM, Prager-Khoutorsky M, Giannakas N, Kaminari A, Fragkouli A, Nader K, Price TJ, Konicek BW, Graff JR, Tzinia AK, Lacaille JC, Sonenberg N. Gkogkas CG, et al. Among authors: cao r. Cell Rep. 2014 Dec 11;9(5):1742-1755. doi: 10.1016/j.celrep.2014.10.064. Epub 2014 Nov 26. Cell Rep. 2014. PMID: 25466251 Free PMC article.
Metformin ameliorates core deficits in a mouse model of fragile X syndrome.
Gantois I, Khoutorsky A, Popic J, Aguilar-Valles A, Freemantle E, Cao R, Sharma V, Pooters T, Nagpal A, Skalecka A, Truong VT, Wiebe S, Groves IA, Jafarnejad SM, Chapat C, McCullagh EA, Gamache K, Nader K, Lacaille JC, Gkogkas CG, Sonenberg N. Gantois I, et al. Among authors: cao r. Nat Med. 2017 Jun;23(6):674-677. doi: 10.1038/nm.4335. Epub 2017 May 15. Nat Med. 2017. PMID: 28504725 Free article.
mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.
Liu D, Stowie A, de Zavalia N, Leise T, Pathak SS, Drewes LR, Davidson AJ, Amir S, Sonenberg N, Cao R. Liu D, et al. Among authors: cao r. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3296-E3304. doi: 10.1073/pnas.1721578115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555746 Free PMC article.
mTOR signaling regulates central and peripheral circadian clock function.
Ramanathan C, Kathale ND, Liu D, Lee C, Freeman DA, Hogenesch JB, Cao R, Liu AC. Ramanathan C, et al. Among authors: cao r. PLoS Genet. 2018 May 11;14(5):e1007369. doi: 10.1371/journal.pgen.1007369. eCollection 2018 May. PLoS Genet. 2018. PMID: 29750810 Free PMC article.
3,131 results