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Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data.
Xiang Y, Luettich K, Martin F, Battey JND, Trivedi K, Neau L, Wong ET, Guedj E, Dulize R, Peric D, Bornand D, Ouadi S, Sierro N, Büttner A, Ivanov NV, Vanscheeuwijck P, Hoeng J, Peitsch MC. Xiang Y, et al. Among authors: martin f. Front Toxicol. 2021 Mar 16;3:634035. doi: 10.3389/ftox.2021.634035. eCollection 2021. Front Toxicol. 2021. PMID: 35295134 Free PMC article.
Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model.
Luettich K, Xiang Y, Iskandar A, Sewer A, Martin F, Talikka M, Vanscheeuwijck P, Berges A, Veljkovic E, Gonzalez-Suarez I, Schlage W, Hoeng J, Peitsch M. Luettich K, et al. Among authors: martin f. Interdiscip Toxicol. 2014 Jun;7(2):73-84. doi: 10.2478/intox-2014-0010. Epub 2014 Nov 15. Interdiscip Toxicol. 2014. PMID: 26109882 Free PMC article.
Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.
Sewer A, Kogel U, Talikka M, Wong ET, Martin F, Xiang Y, Guedj E, Ivanov NV, Hoeng J, Peitsch MC. Sewer A, et al. Among authors: martin f. Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S82-S92. doi: 10.1016/j.yrtph.2016.11.018. Epub 2016 Nov 17. Regul Toxicol Pharmacol. 2016. PMID: 27866933 Free article.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.
Titz B, Kogel U, Martin F, Schlage WK, Xiang Y, Nury C, Dijon S, Baumer K, Peric D, Bornand D, Dulize R, Phillips B, Leroy P, Vuillaume G, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Titz B, et al. Among authors: martin f. Food Chem Toxicol. 2018 May;115:284-301. doi: 10.1016/j.fct.2018.02.058. Epub 2018 Mar 13. Food Chem Toxicol. 2018. PMID: 29545142 Free article.
Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.
Iskandar AR, Martinez Y, Martin F, Schlage WK, Leroy P, Sewer A, Torres LO, Majeed S, Merg C, Trivedi K, Guedj E, Frentzel S, Mathis C, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: martin f. Toxicol Res (Camb). 2017 Sep 28;6(6):930-946. doi: 10.1039/c7tx00152e. eCollection 2017 Nov 1. Toxicol Res (Camb). 2017. PMID: 30090554 Free PMC article.
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.
Lee KM, Hoeng J, Harbo S, Kogel U, Gardner W, Oldham M, Benson E, Talikka M, Kondylis A, Martin F, Titz B, Ansari S, Trivedi K, Guedj E, Elamin A, Ivanov NV, Vanscheeuwijck P, Peitsch MC, McKinney WJ Jr. Lee KM, et al. Among authors: martin f. Inhal Toxicol. 2018 Nov-Dec;30(13-14):553-567. doi: 10.1080/08958378.2019.1576807. Epub 2019 Mar 8. Inhal Toxicol. 2018. PMID: 30849254
Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.
Titz B, Sewer A, Luettich K, Wong ET, Guedj E, Nury C, Schneider T, Xiang Y, Trivedi K, Vuillaume G, Leroy P, Büttner A, Martin F, Ivanov NV, Vanscheeuwijck P, Hoeng J, Peitsch MC. Titz B, et al. Among authors: martin f. Toxicol Sci. 2020 Nov 1;178(1):138-158. doi: 10.1093/toxsci/kfaa132. Toxicol Sci. 2020. PMID: 32780831 Free PMC article.
4,462 results