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Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy.
Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, McGrath J, Sheppard AD, Hayes C, King R, Temperley H, MacLean M, Bulter C, Bhardwaj A, Moore J, Donohoe C, Ravi N, Conroy MJ, Reynolds JV, Lysaght J. Davern M, et al. Among authors: gaughan c. J Cancer Res Clin Oncol. 2023 Jul;149(8):5377-5395. doi: 10.1007/s00432-022-04440-0. Epub 2022 Nov 29. J Cancer Res Clin Oncol. 2023. PMID: 36445478 Free PMC article.
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients.
Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, Habash M, Sheppard AD, MacLean M, Dunne MR, Moore J, Temperley H, Conroy MJ, Butler C, Bhardwaj A, Ravi N, Donohoe CL, Reynolds JV, Lysaght J. Davern M, et al. Among authors: gaughan c. Cancer Immunol Immunother. 2023 Jan;72(1):55-71. doi: 10.1007/s00262-022-03228-y. Epub 2022 Jun 16. Cancer Immunol Immunother. 2023. PMID: 35708739 Free PMC article.
PD-1 blockade attenuates surgery-mediated immunosuppression and boosts Th1 immunity perioperatively in oesophagogastric junctional adenocarcinoma.
Davern M, Gaughan C, O' Connell F, Moran B, Mylod E, Sheppard AD, Ramjit S, Yun-Tong Kung J, Phelan JJ, Davey MG, Ryan EJ, Butler C, Quinn L, Howard C, Tone E, Phoenix E, Butt WT, Lynam-Lennon N, Maher SG, Ravi N, Donohoe CL, Reynolds JV, Lysaght J, Donlon NE. Davern M, et al. Among authors: gaughan c. Front Immunol. 2023 Jun 9;14:1150754. doi: 10.3389/fimmu.2023.1150754. eCollection 2023. Front Immunol. 2023. PMID: 37359545 Free PMC article.
Analysing the Combined Effects of Radiotherapy and Chemokine Receptor 5 Antagonism: Complementary Approaches to Promote T Cell Function and Migration in Oesophageal Adenocarcinoma.
Davern M, O' Donovan C, Donlon NE, Mylod E, Gaughan C, Bhardwaj A, Sheppard AD, Bracken-Clarke D, Butler C, Ravi N, Donohoe CL, Reynolds JV, Lysaght J, Conroy MJ. Davern M, et al. Among authors: gaughan c. Biomedicines. 2024 Apr 8;12(4):819. doi: 10.3390/biomedicines12040819. Biomedicines. 2024. PMID: 38672174 Free PMC article.
SARS-CoV-2, influenza A/B and respiratory syncytial virus positivity and association with influenza-like illness and self-reported symptoms, over the 2022/23 winter season in the UK: a longitudinal surveillance cohort.
Dietz E, Pritchard E, Pouwels K, Ehsaan M, Blake J, Gaughan C, Haduli E, Boothe H, Vihta KD, Peto T, Stoesser N, Matthews P, Taylor N, Diamond I, Studley R, Rourke E, Birrell P, De Angelis D, Fowler T, Watson C, Eyre D, House T, Walker AS. Dietz E, et al. Among authors: gaughan c. BMC Med. 2024 Mar 26;22(1):143. doi: 10.1186/s12916-024-03351-w. BMC Med. 2024. PMID: 38532381 Free PMC article.
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