White MPJ - Search Results

1

The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF).

Varyani F, Löser S, Filbey KJ, Harcus Y, Drurey C, Poveda MC, Rasid O, White MPJ, Smyth DJ, Gerbe F, Jay P, Maizels RM. Varyani F, et al. Among authors: white mpj. Mucosal Immunol. 2022 Jun;15(6):1243-1256. doi: 10.1038/s41385-022-00496-w. Epub 2022 Mar 14. Mucosal Immunol. 2022. PMID: 35288645 Free PMC article.

2

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM. Johnston CJC, et al. Among authors: white mpj. Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6. Nat Commun. 2017. PMID: 29170498 Free PMC article.

3

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus.

Smyth DJ, Harcus Y, White MPJ, Gregory WF, Nahler J, Stephens I, Toke-Bjolgerud E, Hewitson JP, Ivens A, McSorley HJ, Maizels RM. Smyth DJ, et al. Among authors: white mpj. Int J Parasitol. 2018 Apr;48(5):379-385. doi: 10.1016/j.ijpara.2017.12.004. Epub 2018 Mar 3. Int J Parasitol. 2018. PMID: 29510118 Free PMC article.

4

Regulatory T-cells in helminth infection: induction, function and therapeutic potential.

White MPJ, McManus CM, Maizels RM. White MPJ, et al. Immunology. 2020 Jul;160(3):248-260. doi: 10.1111/imm.13190. Epub 2020 Apr 19. Immunology. 2020. PMID: 32153025 Free PMC article. Review.

5

The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner.

White MPJ, Johnston CJC, Grainger JR, Konkel JE, O'Connor RA, Anderton SM, Maizels RM. White MPJ, et al. Front Immunol. 2020 Sep 29;11:1830. doi: 10.3389/fimmu.2020.01830. eCollection 2020. Front Immunol. 2020. PMID: 33117327 Free PMC article.

6

Induction of stable human FOXP3⁺ Tregs by a parasite-derived TGF-β mimic.

Cook L, Reid KT, Häkkinen E, de Bie B, Tanaka S, Smyth DJ, White MP, Wong MQ, Huang Q, Gillies JK, Ziegler SF, Maizels RM, Levings MK. Cook L, et al. Immunol Cell Biol. 2021 Sep;99(8):833-847. doi: 10.1111/imcb.12475. Epub 2021 Jun 3. Immunol Cell Biol. 2021. PMID: 33929751 Free PMC article.

7

The parasite cytokine mimic Hp-TGM potently replicates the regulatory effects of TGF-β on murine CD4⁺ T cells.

White MPJ, Smyth DJ, Cook L, Ziegler SF, Levings MK, Maizels RM. White MPJ, et al. Immunol Cell Biol. 2021 Sep;99(8):848-864. doi: 10.1111/imcb.12479. Epub 2021 Jul 1. Immunol Cell Biol. 2021. PMID: 33988885 Free PMC article.

8

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Oftedal BE, Maio S, Handel AE, White MPJ, Howie D, Davis S, Prevot N, Rota IA, Deadman ME, Kessler BM, Fischer R, Trede NS, Sezgin E, Maizels RM, Holländer GA. Oftedal BE, et al. Among authors: white mpj. Commun Biol. 2021 Jun 3;4(1):681. doi: 10.1038/s42003-021-02203-0. Commun Biol. 2021. PMID: 34083746 Free PMC article.

9

Oral delivery of a functional algal-expressed TGF-β mimic halts colitis in a murine DSS model.

Smyth DJ, Ren B, White MPJ, McManus C, Webster H, Shek V, Evans C, Pandhal J, Fields F, Maizels RM, Mayfield S. Smyth DJ, et al. Among authors: white mpj. J Biotechnol. 2021 Nov 10;340:1-12. doi: 10.1016/j.jbiotec.2021.08.006. Epub 2021 Aug 12. J Biotechnol. 2021. PMID: 34390759 Free PMC article.

10

Protection from T cell-dependent colitis by the helminth-derived immunomodulatory mimic of transforming growth factor-β, Hp-TGM.

Smyth DJ, White MPJ, Johnston CJC, Donachie AM, Campillo Poveda M, McSorley HJ, Maizels RM. Smyth DJ, et al. Among authors: white mpj. Discov Immunol. 2023 Jan 18;2(1):kyad001. doi: 10.1093/discim/kyad001. eCollection 2023. Discov Immunol. 2023. PMID: 36855464 Free PMC article.

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