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Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo.
Yue P, Zhu Y, Brotherton-Pleiss C, Fu W, Verma N, Chen J, Nakamura K, Chen W, Chen Y, Alonso-Valenteen F, Mikhael S, Medina-Kauwe L, Kershaw KM, Celeridad M, Pan S, Limpert AS, Sheffler DJ, Cosford NDP, Shiao SL, Tius MA, Lopez-Tapia F, Turkson J. Yue P, et al. Among authors: verma n. Cancer Lett. 2022 May 28;534:215613. doi: 10.1016/j.canlet.2022.215613. Epub 2022 Mar 9. Cancer Lett. 2022. PMID: 35276290 Free PMC article.
Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3.
Chen Y, Zhai N, Zhu Y, Yue P, Verma N, Brotherton-Pleiss C, Fu W, Nakamura K, Chen W, Kawakami J, Murali R, Tius MA, Lopez-Tapia F, Turkson J. Chen Y, et al. Among authors: verma n. Bioorg Med Chem Lett. 2024 Jan 1;97:129565. doi: 10.1016/j.bmcl.2023.129565. Epub 2023 Nov 24. Bioorg Med Chem Lett. 2024. PMID: 38008341 Free article. No abstract available.
Range of the perfluorooctanoate (PFOA) safe dose for human health: An international collaboration.
Burgoon LD, Clewell HJ, Cox T, Dekant W, Dell LD, Deyo JA, Dourson ML, Gadagbui BK, Goodrum P, Green LC, Vijayavel K, Kline TR, House-Knight T, Luster MI, Manning T, Nathanail P, Pagone F, Richardson K, Severo-Peixe T, Sharma A, Smith JS, Verma N, Wright J. Burgoon LD, et al. Among authors: verma n. Regul Toxicol Pharmacol. 2023 Dec;145:105502. doi: 10.1016/j.yrtph.2023.105502. Epub 2023 Oct 29. Regul Toxicol Pharmacol. 2023. PMID: 38832926
2,225 results