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Nucleolar-based Dux repression is essential for embryonic two-cell stage exit.
Xie SQ, Leeke BJ, Whilding C, Wagner RT, Garcia-Llagostera F, Low Y, Chammas P, Cheung NT, Dormann D, McManus MT, Percharde M. Xie SQ, et al. Among authors: whilding c. Genes Dev. 2022 Mar 1;36(5-6):331-347. doi: 10.1101/gad.349172.121. Epub 2022 Mar 10. Genes Dev. 2022. PMID: 35273077 Free PMC article.
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.
Robles-Rebollo I, Cuartero S, Canellas-Socias A, Wells S, Karimi MM, Mereu E, Chivu AG, Heyn H, Whilding C, Dormann D, Marguerat S, Rioja I, Prinjha RK, Stumpf MPH, Fisher AG, Merkenschlager M. Robles-Rebollo I, et al. Among authors: whilding c. Nat Commun. 2022 Jul 27;13(1):4342. doi: 10.1038/s41467-022-31192-9. Nat Commun. 2022. PMID: 35896525 Free PMC article.
Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction.
Djeghloul D, Patel B, Kramer H, Dimond A, Whilding C, Brown K, Kohler AC, Feytout A, Veland N, Elliott J, Bharat TAM, Tarafder AK, Löwe J, Ng BL, Guo Y, Guy J, Huseyin MK, Klose RJ, Merkenschlager M, Fisher AG. Djeghloul D, et al. Among authors: whilding c. Nat Commun. 2020 Aug 17;11(1):4118. doi: 10.1038/s41467-020-17823-z. Nat Commun. 2020. PMID: 32807789 Free PMC article.
Cohesin-dependence of neuronal gene expression relates to chromatin loop length.
Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M. Calderon L, et al. Among authors: whilding c. Elife. 2022 Apr 26;11:e76539. doi: 10.7554/eLife.76539. Elife. 2022. PMID: 35471149 Free PMC article.
AMPK activation protects against prostate cancer by inducing a catabolic cellular state.
Penfold L, Woods A, Pollard AE, Arizanova J, Pascual-Navarro E, Muckett PJ, Dore MH, Montoya A, Whilding C, Fets L, Mokochinski J, Constantin TA, Varela-Carver A, Leach DA, Bevan CL, Nikitin AY, Hall Z, Carling D. Penfold L, et al. Among authors: whilding c. Cell Rep. 2023 Apr 25;42(4):112396. doi: 10.1016/j.celrep.2023.112396. Epub 2023 Apr 15. Cell Rep. 2023. PMID: 37061917 Free PMC article.
17 results