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The current toolbox for APOBEC drug discovery.
Grillo MJ, Jones KFM, Carpenter MA, Harris RS, Harki DA. Grillo MJ, et al. Among authors: harris rs. Trends Pharmacol Sci. 2022 May;43(5):362-377. doi: 10.1016/j.tips.2022.02.007. Trends Pharmacol Sci. 2022. PMID: 35272863 Free PMC article. Review.
Retroviral restriction by APOBEC proteins.
Harris RS, Liddament MT. Harris RS, et al. Nat Rev Immunol. 2004 Nov;4(11):868-77. doi: 10.1038/nri1489. Nat Rev Immunol. 2004. PMID: 15516966 Review.
Enhancing immunity to HIV through APOBEC.
Harris RS. Harris RS. Nat Biotechnol. 2008 Oct;26(10):1089-90. doi: 10.1038/nbt1008-1089. Nat Biotechnol. 2008. PMID: 18846074 No abstract available.
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G.
Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, Schiffer CA, Harris RS. Li M, et al. Among authors: harris rs. ACS Chem Biol. 2012 Mar 16;7(3):506-17. doi: 10.1021/cb200440y. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22181350 Free PMC article.
APOBEC3B is an enzymatic source of mutation in breast cancer.
Burns MB, Lackey L, Carpenter MA, Rathore A, Land AM, Leonard B, Refsland EW, Kotandeniya D, Tretyakova N, Nikas JB, Yee D, Temiz NA, Donohue DE, McDougle RM, Brown WL, Law EK, Harris RS. Burns MB, et al. Among authors: harris rs. Nature. 2013 Feb 21;494(7437):366-70. doi: 10.1038/nature11881. Epub 2013 Feb 6. Nature. 2013. PMID: 23389445 Free PMC article.
515 results