High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.
Ketley A, Chen CZ, Li X, Arya S, Robinson TE, Granados-Riveron J, Udosen I, Morris GE, Holt I, Furling D, Chaouch S, Haworth B, Southall N, Shinn P, Zheng W, Austin CP, Hayes CJ, Brook JD.
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Hum Mol Genet. 2014 Mar 15;23(6):1551-62. doi: 10.1093/hmg/ddt542. Epub 2013 Oct 30.
Hum Mol Genet. 2014.
PMID: 24179176
Free PMC article.