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93 results

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Page 1
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia.
Barreyro L, Sampson AM, Ishikawa C, Hueneman KM, Choi K, Pujato MA, Chutipongtanate S, Wyder M, Haffey WD, O'Brien E, Wunderlich M, Ramesh V, Kolb EM, Meydan C, Neelamraju Y, Bolanos LC, Christie S, Smith MA, Niederkorn M, Muto T, Kesari S, Garrett-Bakelman FE, Bartholdy B, Will B, Weirauch MT, Mulloy JC, Gul Z, Medlin S, Kovall RA, Melnick AM, Perentesis JP, Greis KD, Nurmemmedov E, Seibel WL, Starczynowski DT. Barreyro L, et al. Among authors: starczynowski dt. Sci Transl Med. 2022 Mar 9;14(635):eabb7695. doi: 10.1126/scitranslmed.abb7695. Epub 2022 Mar 9. Sci Transl Med. 2022. PMID: 35263148
Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1.
Fang J, Rhyasen G, Bolanos L, Rasch C, Varney M, Wunderlich M, Goyama S, Jansen G, Cloos J, Rigolino C, Cortelezzi A, Mulloy JC, Oliva EN, Cuzzola M, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Blood. 2012 Jul 26;120(4):858-67. doi: 10.1182/blood-2012-02-407999. Epub 2012 Jun 8. Blood. 2012. PMID: 22685174 Free PMC article.
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.
Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Cancer Cell. 2013 Jul 8;24(1):90-104. doi: 10.1016/j.ccr.2013.05.006. Cancer Cell. 2013. PMID: 23845443 Free PMC article.
Differential IRAK signaling in hematologic malignancies.
Rhyasen GW, Bolanos L, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Exp Hematol. 2013 Dec;41(12):1005-7. doi: 10.1016/j.exphem.2013.09.008. Epub 2013 Sep 29. Exp Hematol. 2013. PMID: 24084080 Free PMC article. No abstract available.
An MDS xenograft model utilizing a patient-derived cell line.
Rhyasen GW, Wunderlich M, Tohyama K, Garcia-Manero G, Mulloy JC, Starczynowski DT. Rhyasen GW, et al. Among authors: starczynowski dt. Leukemia. 2014 May;28(5):1142-5. doi: 10.1038/leu.2013.372. Epub 2013 Dec 11. Leukemia. 2014. PMID: 24326684 Free PMC article. No abstract available.
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network.
Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. Fang J, et al. Among authors: starczynowski dt. Cell Rep. 2014 Sep 11;8(5):1328-38. doi: 10.1016/j.celrep.2014.07.062. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199827 Free PMC article.
Deconstructing innate immune signaling in myelodysplastic syndromes.
Varney ME, Melgar K, Niederkorn M, Smith M, Barreyro L, Starczynowski DT. Varney ME, et al. Among authors: starczynowski dt. Exp Hematol. 2015 Aug;43(8):587-598. doi: 10.1016/j.exphem.2015.05.016. Epub 2015 Jul 2. Exp Hematol. 2015. PMID: 26143580 Free PMC article. Review.
MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia.
Gentner B, Pochert N, Rouhi A, Boccalatte F, Plati T, Berg T, Sun SM, Mah SM, Mirkovic-Hösle M, Ruschmann J, Muranyi A, Leierseder S, Argiropoulos B, Starczynowski DT, Karsan A, Heuser M, Hogge D, Camargo FD, Engelhardt S, Döhner H, Buske C, Jongen-Lavrencic M, Naldini L, Humphries RK, Kuchenbauer F. Gentner B, et al. Among authors: starczynowski dt. Exp Hematol. 2015 Oct;43(10):858-868.e7. doi: 10.1016/j.exphem.2015.05.018. Epub 2015 Jul 8. Exp Hematol. 2015. PMID: 26163797 Free PMC article.
Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.
Varney ME, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, Akiyama T, Christie S, Fang J, Miller D, Jerez A, Karsan A, Maciejewski JP, Meetei RA, Inoue J, Starczynowski DT. Varney ME, et al. Among authors: starczynowski dt. J Exp Med. 2015 Oct 19;212(11):1967-85. doi: 10.1084/jem.20141898. Epub 2015 Oct 12. J Exp Med. 2015. PMID: 26458771 Free PMC article.
93 results