Renslo AR - Search Results

1

Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors.

Jiang H, Muir RK, Gonciarz RL, Olshen AB, Yeh I, Hann BC, Zhao N, Wang YH, Behr SC, Korkola JE, Evans MJ, Collisson EA, Renslo AR. Jiang H, et al. Among authors: renslo ar. J Exp Med. 2022 Apr 4;219(4):e20210739. doi: 10.1084/jem.20210739. Epub 2022 Mar 9. J Exp Med. 2022. PMID: 35262628 Free PMC article.

2

Pharmacological brake-release of mRNA translation enhances cognitive memory.

Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Sidrauski C, et al. Among authors: renslo ar. Elife. 2013 May 28;2:e00498. doi: 10.7554/eLife.00498. Elife. 2013. PMID: 23741617 Free PMC article.

3

A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models.

Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. Spangler B, et al. Among authors: renslo ar. J Med Chem. 2016 Dec 22;59(24):11161-11170. doi: 10.1021/acs.jmedchem.6b01470. Epub 2016 Dec 12. J Med Chem. 2016. PMID: 27936709 Free PMC article.

4

cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool.

Camarena V, Sant DW, Huff TC, Mustafi S, Muir RK, Aron AT, Chang CJ, Renslo AR, Monje PV, Wang G. Camarena V, et al. Among authors: renslo ar. Elife. 2017 Dec 14;6:e29750. doi: 10.7554/eLife.29750. Elife. 2017. PMID: 29239726 Free PMC article.

5

Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography.

Muir RK, Zhao N, Wei J, Wang YH, Moroz A, Huang Y, Chen YC, Sriram R, Kurhanewicz J, Ruggero D, Renslo AR, Evans MJ. Muir RK, et al. Among authors: renslo ar. ACS Cent Sci. 2019 Apr 24;5(4):727-736. doi: 10.1021/acscentsci.9b00240. Epub 2019 Apr 3. ACS Cent Sci. 2019. PMID: 31041393 Free PMC article.

6

Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor.

Blank BR, Talukder P, Muir RK, Green ER, Skaar EP, Renslo AR. Blank BR, et al. Among authors: renslo ar. ACS Infect Dis. 2019 Aug 9;5(8):1366-1375. doi: 10.1021/acsinfecdis.9b00057. Epub 2019 Jun 11. ACS Infect Dis. 2019. PMID: 31140267 Free PMC article.

7

Oscillatory cAMP signaling rapidly alters H3K4 methylation.

Huff TC, Camarena V, Sant DW, Wilkes Z, Van Booven D, Aron AT, Muir RK, Renslo AR, Chang CJ, Monje PV, Wang G. Huff TC, et al. Among authors: renslo ar. Life Sci Alliance. 2019 Dec 27;3(1):e201900529. doi: 10.26508/lsa.201900529. Print 2020 Jan. Life Sci Alliance. 2019. PMID: 31882444 Free PMC article.

8

Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy.

Blank BR, Gonciarz RL, Talukder P, Gut J, Legac J, Rosenthal PJ, Renslo AR. Blank BR, et al. Among authors: renslo ar. ACS Infect Dis. 2020 Jul 10;6(7):1827-1835. doi: 10.1021/acsinfecdis.0c00064. Epub 2020 May 18. ACS Infect Dis. 2020. PMID: 32369341 Free PMC article.

9

Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.

Zhao N, Huang Y, Wang YH, Muir RK, Chen YC, Wei J, Hooshdaran N, Viswanath P, Seo Y, Ruggero D, Renslo AR, Evans MJ. Zhao N, et al. Among authors: renslo ar. J Nucl Med. 2021 Jul 1;62(7):949-955. doi: 10.2967/jnumed.120.252460. Epub 2020 Nov 27. J Nucl Med. 2021. PMID: 33246980 Free PMC article.

10

Ferrous Iron-Dependent Pharmacology.

Gonciarz RL, Collisson EA, Renslo AR. Gonciarz RL, et al. Among authors: renslo ar. Trends Pharmacol Sci. 2021 Jan;42(1):7-18. doi: 10.1016/j.tips.2020.11.003. Epub 2020 Nov 28. Trends Pharmacol Sci. 2021. PMID: 33261861 Free PMC article. Review.

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