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Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes.
Goñi GM, Epifano C, Boskovic J, Camacho-Artacho M, Zhou J, Bronowska A, Martín MT, Eck MJ, Kremer L, Gräter F, Gervasio FL, Perez-Moreno M, Lietha D. Goñi GM, et al. Among authors: grater f. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3177-86. doi: 10.1073/pnas.1317022111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049397 Free PMC article.
Mechanism of Focal Adhesion Kinase Mechanosensing.
Zhou J, Aponte-Santamaría C, Sturm S, Bullerjahn JT, Bronowska A, Gräter F. Zhou J, et al. Among authors: grater f. PLoS Comput Biol. 2015 Nov 6;11(11):e1004593. doi: 10.1371/journal.pcbi.1004593. eCollection 2015 Nov. PLoS Comput Biol. 2015. PMID: 26544178 Free PMC article.
Structural and mechanistic insights into mechanoactivation of focal adhesion kinase.
Bauer MS, Baumann F, Daday C, Redondo P, Durner E, Jobst MA, Milles LF, Mercadante D, Pippig DA, Gaub HE, Gräter F, Lietha D. Bauer MS, et al. Among authors: grater f. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6766-6774. doi: 10.1073/pnas.1820567116. Epub 2019 Mar 15. Proc Natl Acad Sci U S A. 2019. PMID: 30877242 Free PMC article.
Mechanoenzymatics of titin kinase.
Puchner EM, Alexandrovich A, Kho AL, Hensen U, Schäfer LV, Brandmeier B, Gräter F, Grubmüller H, Gaub HE, Gautel M. Puchner EM, et al. Among authors: grater f. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13385-90. doi: 10.1073/pnas.0805034105. Epub 2008 Sep 2. Proc Natl Acad Sci U S A. 2008. PMID: 18765796 Free PMC article.
Protein mechanics: how force regulates molecular function.
Seifert C, Gräter F. Seifert C, et al. Among authors: grater f. Biochim Biophys Acta. 2013 Oct;1830(10):4762-8. doi: 10.1016/j.bbagen.2013.06.005. Epub 2013 Jun 19. Biochim Biophys Acta. 2013. PMID: 23791949 Review.
128 results