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Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.
Monian P, Shivalila C, Lu G, Shimizu M, Boulay D, Bussow K, Byrne M, Bezigian A, Chatterjee A, Chew D, Desai J, Favaloro F, Godfrey J, Hoss A, Iwamoto N, Kawamoto T, Kumarasamy J, Lamattina A, Lindsey A, Liu F, Looby R, Marappan S, Metterville J, Murphy R, Rossi J, Pu T, Bhattarai B, Standley S, Tripathi S, Yang H, Yin Y, Yu H, Zhou C, Apponi LH, Kandasamy P, Vargeese C. Monian P, et al. Among authors: boulay d. Nat Biotechnol. 2022 Jul;40(7):1093-1102. doi: 10.1038/s41587-022-01225-1. Epub 2022 Mar 7. Nat Biotechnol. 2022. PMID: 35256816
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Kandasamy P, Liu Y, Aduda V, Akare S, Alam R, Andreucci A, Boulay D, Bowman K, Byrne M, Cannon M, Chivatakarn O, Shelke JD, Iwamoto N, Kawamoto T, Kumarasamy J, Lamore S, Lemaitre M, Lin X, Longo K, Looby R, Marappan S, Metterville J, Mohapatra S, Newman B, Paik IH, Patil S, Purcell-Estabrook E, Shimizu M, Shum P, Standley S, Taborn K, Tripathi S, Yang H, Yin Y, Zhao X, Dale E, Vargeese C. Kandasamy P, et al. Among authors: boulay d. Nucleic Acids Res. 2022 Jun 10;50(10):5401-5423. doi: 10.1093/nar/gkac037. Nucleic Acids Res. 2022. PMID: 35106589 Free PMC article.
Serologic Testing of US Blood Donations to Identify Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Reactive Antibodies: December 2019-January 2020.
Basavaraju SV, Patton ME, Grimm K, Rasheed MAU, Lester S, Mills L, Stumpf M, Freeman B, Tamin A, Harcourt J, Schiffer J, Semenova V, Li H, Alston B, Ategbole M, Bolcen S, Boulay D, Browning P, Cronin L, David E, Desai R, Epperson M, Gorantla Y, Jia T, Maniatis P, Moss K, Ortiz K, Park SH, Patel P, Qin Y, Steward-Clark E, Tatum H, Vogan A, Zellner B, Drobeniuc J, Sapiano MRP, Havers F, Reed C, Gerber S, Thornburg NJ, Stramer SL. Basavaraju SV, et al. Among authors: boulay d. Clin Infect Dis. 2021 Jun 15;72(12):e1004-e1009. doi: 10.1093/cid/ciaa1785. Clin Infect Dis. 2021. PMID: 33252659 Free PMC article.
Decline in SARS-CoV-2 Antibodies After Mild Infection Among Frontline Health Care Personnel in a Multistate Hospital Network - 12 States, April-August 2020.
Self WH, Tenforde MW, Stubblefield WB, Feldstein LR, Steingrub JS, Shapiro NI, Ginde AA, Prekker ME, Brown SM, Peltan ID, Gong MN, Aboodi MS, Khan A, Exline MC, Files DC, Gibbs KW, Lindsell CJ, Rice TW, Jones ID, Halasa N, Talbot HK, Grijalva CG, Casey JD, Hager DN, Qadir N, Henning DJ, Coughlin MM, Schiffer J, Semenova V, Li H, Thornburg NJ, Patel MM; CDC COVID-19 Response Team; IVY Network. Self WH, et al. MMWR Morb Mortal Wkly Rep. 2020 Nov 27;69(47):1762-1766. doi: 10.15585/mmwr.mm6947a2. MMWR Morb Mortal Wkly Rep. 2020. PMID: 33237893 Free PMC article.
Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model.
Do TM, Capdevila C, Pradier L, Blanchard V, Lopez-Grancha M, Schussler N, Steinmetz A, Beninga J, Boulay D, Dugay P, Verdier P, Aubin N, Dargazanli G, Chaves C, Genet E, Lossouarn Y, Loux C, Michoux F, Moindrot N, Chanut F, Gury T, Eyquem S, Valente D, Bergis O, Rao E, Lesuisse D. Do TM, et al. Among authors: boulay d. Mol Ther Methods Clin Dev. 2020 Aug 21;19:58-77. doi: 10.1016/j.omtm.2020.08.014. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33005703 Free PMC article.
Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab.
Chemello K, Beeské S, Trang Tran TT, Blanchard V, Villard EF, Poirier B, Le Bail JC, Dargazanli G, Ho-Van-Guimbal S, Boulay D, Bergis O, Pruniaux MP, Croyal M, Janiak P, Guillot E, Lambert G. Chemello K, et al. Among authors: boulay d. JACC Basic Transl Sci. 2020 May 6;5(6):549-557. doi: 10.1016/j.jacbts.2020.03.008. eCollection 2020 Jun. JACC Basic Transl Sci. 2020. PMID: 32613143 Free PMC article.
The selective GSK3 inhibitor, SAR502250, displays neuroprotective activity and attenuates behavioral impairments in models of neuropsychiatric symptoms of Alzheimer's disease in rodents.
Griebel G, Stemmelin J, Lopez-Grancha M, Boulay D, Boquet G, Slowinski F, Pichat P, Beeské S, Tanaka S, Mori A, Fujimura M, Eguchi J. Griebel G, et al. Among authors: boulay d. Sci Rep. 2019 Dec 2;9(1):18045. doi: 10.1038/s41598-019-54557-5. Sci Rep. 2019. PMID: 31792284 Free PMC article.
The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia.
Griebel G, Pichat P, Boulay D, Naimoli V, Potestio L, Featherstone R, Sahni S, Defex H, Desvignes C, Slowinski F, Vigé X, Bergis OE, Sher R, Kosley R, Kongsamut S, Black MD, Varty GB. Griebel G, et al. Among authors: boulay d. Sci Rep. 2016 Oct 13;6:35320. doi: 10.1038/srep35320. Sci Rep. 2016. PMID: 27734956 Free PMC article.
Anthrax Toxin-Expressing Bacillus cereus Isolated from an Anthrax-Like Eschar.
Marston CK, Ibrahim H, Lee P, Churchwell G, Gumke M, Stanek D, Gee JE, Boyer AE, Gallegos-Candela M, Barr JR, Li H, Boulay D, Cronin L, Quinn CP, Hoffmaster AR. Marston CK, et al. Among authors: boulay d. PLoS One. 2016 Jun 3;11(6):e0156987. doi: 10.1371/journal.pone.0156987. eCollection 2016. PLoS One. 2016. PMID: 27257909 Free PMC article.
41 results