Seymour LW - Search Results

1

Self-attenuating adenovirus enables production of recombinant adeno-associated virus for high manufacturing yield without contamination.

Su W, Patrício MI, Duffy MR, Krakowiak JM, Seymour LW, Cawood R. Su W, et al. Among authors: seymour lw. Nat Commun. 2022 Mar 7;13(1):1182. doi: 10.1038/s41467-022-28738-2. Nat Commun. 2022. PMID: 35256603 Free PMC article.

2

Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera.

Carlisle RC, Benjamin R, Briggs SS, Sumner-Jones S, McIntosh J, Gill D, Hyde S, Nathwani A, Subr V, Ulbrich K, Seymour LW, Fisher KD. Carlisle RC, et al. Among authors: seymour lw. J Gene Med. 2008 Apr;10(4):400-11. doi: 10.1002/jgm.1161. J Gene Med. 2008. PMID: 18220318

3

Toward more effective gene delivery.

Chen HH, Cawood R, Seymour LW. Chen HH, et al. Among authors: seymour lw. Genome Biol. 2008 Jan 18;9(1):301. doi: 10.1186/gb-2008-9-1-301. Genome Biol. 2008. PMID: 18226177 Free PMC article.

4

Cellular carriers or free viruses?

Seymour LW, Cawood R, Fisher KD. Seymour LW, et al. Curr Opin Mol Ther. 2008 Aug;10(4):321-2. Curr Opin Mol Ther. 2008. PMID: 18683095 No abstract available.

5

Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells.

Cawood R, Chen HH, Carroll F, Bazan-Peregrino M, van Rooijen N, Seymour LW. Cawood R, et al. Among authors: seymour lw. PLoS Pathog. 2009 May;5(5):e1000440. doi: 10.1371/journal.ppat.1000440. Epub 2009 May 22. PLoS Pathog. 2009. PMID: 19461878 Free PMC article.

6

Blood compatibility of enveloped viruses.

Kueberuwa G, Cawood R, Seymour LW. Kueberuwa G, et al. Among authors: seymour lw. Curr Opin Mol Ther. 2010 Aug;12(4):412-20. Curr Opin Mol Ther. 2010. PMID: 20677092 Review.

7

Active adenoviral vascular penetration by targeted formation of heterocellular endothelial-epithelial syncytia.

Chen HH, Cawood R, El-Sherbini Y, Purdie L, Bazan-Peregrino M, Seymour LW, Carlisle RC. Chen HH, et al. Among authors: seymour lw. Mol Ther. 2011 Jan;19(1):67-75. doi: 10.1038/mt.2010.209. Epub 2010 Sep 28. Mol Ther. 2011. PMID: 20877345 Free PMC article.

8

MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity.

Cawood R, Wong SL, Di Y, Baban DF, Seymour LW. Cawood R, et al. Among authors: seymour lw. PLoS One. 2011 Jan 10;6(1):e16152. doi: 10.1371/journal.pone.0016152. PLoS One. 2011. PMID: 21264344 Free PMC article.

9

Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway.

Seki T, Carroll F, Illingworth S, Green N, Cawood R, Bachtarzi H, Subr V, Fisher KD, Seymour LW. Seki T, et al. Among authors: seymour lw. J Control Release. 2011 Dec 20;156(3):381-9. doi: 10.1016/j.jconrel.2011.08.022. Epub 2011 Aug 22. J Control Release. 2011. PMID: 21884739

10

Virotherapy--cancer targeted pharmacology.

Tedcastle A, Cawood R, Di Y, Fisher KD, Seymour LW. Tedcastle A, et al. Among authors: seymour lw. Drug Discov Today. 2012 Mar;17(5-6):215-20. doi: 10.1016/j.drudis.2011.12.011. Epub 2011 Dec 16. Drug Discov Today. 2012. PMID: 22198165 Review.

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