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Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cp rat model of prediabetic metabolic syndrome.
Russell JC, Kelly SE, Diane A, Wang Y, Mangat R, Novak S, Vine DF, Proctor SD. Russell JC, et al. Among authors: proctor sd. Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G507-16. doi: 10.1152/ajpgi.00173.2010. Epub 2010 May 27. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20508159 Free article.
Increased risk of cardiovascular disease in Type 1 diabetes: arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans.
Mangat R, Su JW, Lambert JE, Clandinin MT, Wang Y, Uwiera RR, Forbes JM, Vine DF, Cooper ME, Mamo JC, Proctor SD. Mangat R, et al. Among authors: proctor sd. Diabet Med. 2011 Jan;28(1):61-72. doi: 10.1111/j.1464-5491.2010.03138.x. Diabet Med. 2011. PMID: 21166847
Arterial retention of remnant lipoproteins ex vivo is increased in insulin resistance because of increased arterial biglycan and production of cholesterol-rich atherogenic particles that can be improved by ezetimibe in the JCR:LA-cp rat.
Mangat R, Warnakula S, Borthwick F, Hassanali Z, Uwiera RR, Russell JC, Cheeseman CI, Vine DF, Proctor SD. Mangat R, et al. Among authors: proctor sd. J Am Heart Assoc. 2012 Oct;1(5):e003434. doi: 10.1161/JAHA.112.003434. Epub 2012 Oct 25. J Am Heart Assoc. 2012. PMID: 23316299 Free PMC article.
129 results