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α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.
Brusco I, Camponogara C, Carvalho FB, Schetinger MRC, Oliveira MS, Trevisan G, Ferreira J, Oliveira SM. Brusco I, et al. Among authors: camponogara c. Br J Pharmacol. 2017 Dec;174(23):4247-4262. doi: 10.1111/bph.13992. Epub 2017 Oct 18. Br J Pharmacol. 2017. PMID: 28849589 Free PMC article.
Topical treatment with a transient receptor potential ankyrin 1 (TRPA1) antagonist reduced nociception and inflammation in a thermal lesion model in rats.
de David Antoniazzi CT, De Prá SD, Ferro PR, Silva MA, Adamante G, de Almeida AS, Camponogara C, da Silva CR, de Bem Silveira G, Silveira PCL, Oliveira SM, Rigo FK, De Logu F, Nassini R, Trevisan G. de David Antoniazzi CT, et al. Among authors: camponogara c. Eur J Pharm Sci. 2018 Dec 1;125:28-38. doi: 10.1016/j.ejps.2018.09.012. Epub 2018 Sep 17. Eur J Pharm Sci. 2018. PMID: 30236550
Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain.
Antoniazzi CTD, Nassini R, Rigo FK, Milioli AM, Bellinaso F, Camponogara C, Silva CR, de Almeida AS, Rossato MF, De Logu F, Oliveira SM, Cunha TM, Geppetti P, Ferreira J, Trevisan G. Antoniazzi CTD, et al. Among authors: camponogara c. Int J Cancer. 2019 Jan 15;144(2):355-365. doi: 10.1002/ijc.31911. Epub 2018 Oct 30. Int J Cancer. 2019. PMID: 30289972 Free PMC article.
Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice.
Brusco I, Li Puma S, Chiepe KB, da Silva Brum E, de David Antoniazzi CT, de Almeida AS, Camponogara C, Silva CR, De Logu F, de Andrade VM, Ferreira J, Geppetti P, Nassini R, Oliveira SM, Trevisan G. Brusco I, et al. Among authors: camponogara c. Int J Cancer. 2020 May 15;146(10):2797-2809. doi: 10.1002/ijc.32648. Epub 2019 Oct 8. Int J Cancer. 2020. PMID: 31456221 Free article.
32 results