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Tenofovir Douche as HIV Preexposure Prophylaxis for Receptive Anal Intercourse: Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics (DREAM 01).
Weld ED, McGowan I, Anton P, Fuchs EJ, Ho K, Carballo-Dieguez A, Rohan LC, Giguere R, Brand R, Edick S, Bakshi RP, Parsons T, Manohar M, Seigel A, Engstrom J, Elliott J, Jacobson C, Bagia C, Wang L, Al-Khouja A, Hartman DJ, Bumpus NN, Spiegel HML, Marzinke MA, Hendrix CW. Weld ED, et al. J Infect Dis. 2024 Apr 12;229(4):1131-1140. doi: 10.1093/infdis/jiad535. J Infect Dis. 2024. PMID: 38019657 Clinical Trial.
Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells.
Brand RM, Moore BA, Zyhowski A, Siegel A, Uttam S, Metter EJ, Engstrom J, Brand RE, Biswas N, Whitcomb DC, Binion DG, Schwartz M, McGowan I. Brand RM, et al. Among authors: brand re. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G396-G410. doi: 10.1152/ajpgi.00383.2020. Epub 2020 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33355506 Free PMC article.
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Mallarino-Haeger C, Abebe KZ, Jackson EK, Zyhowski A, Klamar-Blain C, Cyktor JC, Comer D, Brand RM, Gillespie DG, Holleran K, Mellors JW, McGowan I, Riddler SA, Macatangay BJC. Mallarino-Haeger C, et al. Among authors: brand rm. J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):665-669. doi: 10.1097/QAI.0000000000002488. J Acquir Immune Defic Syndr. 2020. PMID: 33177477 Free PMC article. Clinical Trial.
Tenofovir, emtricitabine, lamivudine and dolutegravir concentrations in plasma and urine following drug intake cessation in a randomized controlled directly observed pharmacokinetic trial to aid point-of-care testing.
Else LJ, Dickinson L, Edick S, Zyhowski A, Ho K, Meyn L, Dilly-Penchala S, Thompson B, Shaw V, Khoo S, Brand RM. Else LJ, et al. Among authors: brand rm. J Antimicrob Chemother. 2024 May 17:dkae147. doi: 10.1093/jac/dkae147. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38758205
A Phase 1 Clinical Trial to Assess the Safety and Pharmacokinetics of a Tenofovir Alafenamide/Elvitegravir Insert Administered Rectally for HIV Prevention.
Riddler SA, Kelly CW, Hoesley CJ, Ho KS, Piper JM, Edick S, Heard F, Doncel GF, Johnson S, Anderson PL, Brand RM, Kunjara Na Ayudhya RP, Bauermeister JA, Hillier SL, Hendrix CW. Riddler SA, et al. Among authors: brand rm. J Infect Dis. 2024 Apr 24:jiae211. doi: 10.1093/infdis/jiae211. Online ahead of print. J Infect Dis. 2024. PMID: 38655842
89 results