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NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, Lackner A, Schoefer C, von Haeseler A, Buecker C, Pauli A, Ameres SL, Smith A, Beyer A, Leeb M. Huth M, et al. Among authors: von haeseler a. Genes Dev. 2022 Mar 1;36(5-6):348-367. doi: 10.1101/gad.347690.120. Epub 2022 Mar 3. Genes Dev. 2022. PMID: 35241478 Free PMC article.
Thiol-linked alkylation of RNA to assess expression dynamics.
Herzog VA, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard TR, Wlotzka W, von Haeseler A, Zuber J, Ameres SL. Herzog VA, et al. Among authors: von haeseler a. Nat Methods. 2017 Dec;14(12):1198-1204. doi: 10.1038/nmeth.4435. Epub 2017 Sep 25. Nat Methods. 2017. PMID: 28945705 Free PMC article.
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis.
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, Rescheneder P, Lipp JJ, Herzog VA, Reichholf B, Cisneros DA, Hoffmann T, Schlapansky MF, Bhat P, von Haeseler A, Köcher T, Obenauf AC, Popow J, Ameres SL, Zuber J. Muhar M, et al. Among authors: von haeseler a. Science. 2018 May 18;360(6390):800-805. doi: 10.1126/science.aao2793. Epub 2018 Apr 5. Science. 2018. PMID: 29622725 Free PMC article.
Exploring the sampling universe of RNA-seq.
Tauber S, von Haeseler A. Tauber S, et al. Among authors: von haeseler a. Stat Appl Genet Mol Biol. 2013 Apr 16;12(2):175-88. doi: 10.1515/sagmb-2012-0049. Stat Appl Genet Mol Biol. 2013. PMID: 23629158
The genomic basis of circadian and circalunar timing adaptations in a midge.
Kaiser TS, Poehn B, Szkiba D, Preussner M, Sedlazeck FJ, Zrim A, Neumann T, Nguyen LT, Betancourt AJ, Hummel T, Vogel H, Dorner S, Heyd F, von Haeseler A, Tessmar-Raible K. Kaiser TS, et al. Among authors: von haeseler a. Nature. 2016 Dec 1;540(7631):69-73. doi: 10.1038/nature20151. Epub 2016 Nov 21. Nature. 2016. PMID: 27871090 Free PMC article.
177 results