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NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, Lackner A, Schoefer C, von Haeseler A, Buecker C, Pauli A, Ameres SL, Smith A, Beyer A, Leeb M. Huth M, et al. Among authors: lackner a. Genes Dev. 2022 Mar 1;36(5-6):348-367. doi: 10.1101/gad.347690.120. Epub 2022 Mar 3. Genes Dev. 2022. PMID: 35241478 Free PMC article.
Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency.
Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M. Lackner A, et al. EMBO J. 2021 Apr 15;40(8):e105776. doi: 10.15252/embj.2020105776. Epub 2021 Mar 9. EMBO J. 2021. PMID: 33687089 Free PMC article.
Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3.
Santini L, Halbritter F, Titz-Teixeira F, Suzuki T, Asami M, Ma X, Ramesmayer J, Lackner A, Warr N, Pauler F, Hippenmeyer S, Laue E, Farlik M, Bock C, Beyer A, Perry ACF, Leeb M. Santini L, et al. Among authors: lackner a. Nat Commun. 2021 Jun 21;12(1):3804. doi: 10.1038/s41467-021-23510-4. Nat Commun. 2021. PMID: 34155196 Free PMC article.
The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate.
Lackner A, Müller M, Gamperl M, Stoeva D, Langmann O, Papuchova H, Roitinger E, Dürnberger G, Imre R, Mechtler K, Latos PA. Lackner A, et al. Nat Commun. 2023 May 4;14(1):2559. doi: 10.1038/s41467-023-38101-8. Nat Commun. 2023. PMID: 37137875 Free PMC article.
MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.
Hornbachner R, Lackner A, Papuchova H, Haider S, Knöfler M, Mechtler K, Latos PA. Hornbachner R, et al. Among authors: lackner a. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2105130118. doi: 10.1073/pnas.2105130118. Proc Natl Acad Sci U S A. 2021. PMID: 34507999 Free PMC article.
380 results