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2'-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity.
Honcharenko D, Rocha CSJ, Lundin KE, Maity J, Milton S, Tedebark U, Murtola M, Honcharenko M, Slaitas A, Smith CIE, Zain R, Strömberg R. Honcharenko D, et al. Among authors: murtola m. Nucleic Acid Ther. 2022 Jun;32(3):221-233. doi: 10.1089/nat.2021.0086. Epub 2022 Mar 2. Nucleic Acid Ther. 2022. PMID: 35238623 Free PMC article.
Making oligonucleotide conjugates and breaking oligonucleotides.
Milton S, Murtola M, Sandbrink J, Yeheskiely E, Strömberg R. Milton S, et al. Among authors: murtola m. Nucleic Acids Symp Ser (Oxf). 2007;(51):61. doi: 10.1093/nass/nrm031. Nucleic Acids Symp Ser (Oxf). 2007. PMID: 18029586
Clamping of RNA with PNA enables targeting of microRNA.
Ghidini A, Bergquist H, Murtola M, Punga T, Zain R, Strömberg R. Ghidini A, et al. Among authors: murtola m. Org Biomol Chem. 2016 Jun 21;14(23):5210-3. doi: 10.1039/c6ob00516k. Epub 2016 May 20. Org Biomol Chem. 2016. PMID: 27203783
RNA cleavage by 2,9-diamino-1,10-phenanthroline PNA conjugates.
Murtola M, Ossipov D, Sandbrink J, Strömberg R. Murtola M, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1479-83. doi: 10.1080/15257770701542769. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066810
22 results